Thomassen M J, Klinger J D, Badger S J, van Heeckeren D W, Stern R C
J Pediatr. 1984 Mar;104(3):352-6. doi: 10.1016/s0022-3476(84)81094-x.
Bacteriologic cultures of sputum and specimens obtained at thoracotomy from 17 patients with cystic fibrosis were compared. All organisms found in the surgical specimens were found in the sputum. Only two surgical specimens failed to yield any organisms. The most frequently isolated organisms were Pseudomonas aeruginosa (41%) and Pseudomonas cepacia (35%). Serotypes of P. aeruginosa and antibiogram results on both P. aeruginosa and P. cepacia further supported the concordance of the isolates from the two sources. In addition, anaerobic cultures were obtained in specimens from 10 patients with CF and revealed two patients with anaerobic colonization of the lower respiratory tract. These findings also correlated well with the sputum cultures. The correlation of sputum and lung specimen culture results supports the value of sputum culture in the management of lung disease in CF.
对17例囊性纤维化患者的痰液和开胸手术获取的标本进行了细菌学培养比较。手术标本中发现的所有微生物在痰液中均有发现。只有两份手术标本未培养出任何微生物。最常分离出的微生物是铜绿假单胞菌（41%）和洋葱伯克霍尔德菌（35%）。铜绿假单胞菌的血清型以及铜绿假单胞菌和洋葱伯克霍尔德菌的抗菌谱结果进一步支持了来自这两个来源的分离株的一致性。此外，对10例囊性纤维化患者的标本进行了厌氧培养，发现2例患者下呼吸道有厌氧菌定植。这些发现也与痰液培养结果密切相关。痰液和肺标本培养结果的相关性支持了痰液培养在囊性纤维化肺部疾病管理中的价值。
