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淋病奈瑟菌的DNA切除修复系统。

A DNA excision repair system for Neisseria gonorrhoeae.

作者信息

Campbell L A, Yasbin R E

出版信息

Mol Gen Genet. 1984;193(3):561-3. doi: 10.1007/BF00382101.

DOI:10.1007/BF00382101
PMID:6423936
Abstract

The removal of pyrimidine dimers from deoxyribonucleic acid of ultraviolet irradiated cultures of Neisseria gonorrhoeae can not be readily ascertained by using radioactively labeled thymidine precursors. However, by adapting the alkaline agarose gel technique of Achey et al. (Photochem Photobiol 29, 305-310, 1979), it was possible to demonstrate that this human pathogen does possess an active excision repair system that functions on pyrimidine dimers.

摘要

利用放射性标记的胸腺嘧啶核苷前体,无法轻易确定从经紫外线照射的淋病奈瑟菌培养物的脱氧核糖核酸中去除嘧啶二聚体的情况。然而,通过采用阿奇等人(《光化学与光生物学》29卷,305 - 310页,1979年)的碱性琼脂糖凝胶技术,有可能证明这种人类病原体确实拥有一个作用于嘧啶二聚体的活性切除修复系统。

相似文献

1
A DNA excision repair system for Neisseria gonorrhoeae.淋病奈瑟菌的DNA切除修复系统。
Mol Gen Genet. 1984;193(3):561-3. doi: 10.1007/BF00382101.
2
Deoxyribonucleic acid repair capacities of Neisseria gonorrhoeae: absence of photoreactivation.淋病奈瑟菌的脱氧核糖核酸修复能力:无光复活作用。
J Bacteriol. 1979 Dec;140(3):1109-11. doi: 10.1128/jb.140.3.1109-1111.1979.
3
Neisseria gonorrhoeae recJ mutants show defects in recombinational repair of alkylated bases and UV-induced pyrimidine dimers.淋病奈瑟菌recJ突变体在烷基化碱基和紫外线诱导的嘧啶二聚体的重组修复中表现出缺陷。
Mol Gen Genet. 2000 Oct;264(3):268-75. doi: 10.1007/s004380000316.
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Direct transformation of Neisseria gonorrhoeae by gel-isolated DNA.
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Mutagenesis of Neisseria gonorrhoeae: absence of error-prone repair.淋病奈瑟菌的诱变:缺乏易错修复。
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Excision repair of pyrimidine dimers in human peripheral blood lymphocytes: comparison between mitogen stimulated and unstimulated cells.人类外周血淋巴细胞中嘧啶二聚体的切除修复:有丝分裂原刺激细胞与未刺激细胞的比较
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引用本文的文献

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Genetic characterization of the nucleotide excision repair system of Neisseria gonorrhoeae.淋病奈瑟菌核苷酸切除修复系统的遗传特征。
J Bacteriol. 2010 Feb;192(3):665-73. doi: 10.1128/JB.01018-09. Epub 2009 Nov 20.
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Use of nfsB, encoding nitroreductase, as a reporter gene to determine the mutational spectrum of spontaneous mutations in Neisseria gonorrhoeae.利用编码硝基还原酶的 nfsB 作为报告基因来确定淋病奈瑟菌自发突变的突变谱。
BMC Microbiol. 2009 Nov 23;9:239. doi: 10.1186/1471-2180-9-239.
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Mutagenesis of Neisseria gonorrhoeae: absence of error-prone repair.

本文引用的文献

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TRANSFORMATION OF BIOCHEMICALLY DEFICIENT STRAINS OF BACILLUS SUBTILIS BY DEOXYRIBONUCLEATE.脱氧核糖核酸对枯草芽孢杆菌生化缺陷菌株的转化
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NEISSERIA GONORRHOEAE. I. VIRULENCE GENETICALLY LINKED TO CLONAL VARIATION.淋病奈瑟菌。一、与克隆变异基因连锁的毒力。
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Inducible repair systems and their implications for toxicology.诱导性修复系统及其毒理学意义。
淋病奈瑟菌的诱变:缺乏易错修复。
J Bacteriol. 1984 Oct;160(1):288-93. doi: 10.1128/jb.160.1.288-293.1984.
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Inducible reactivation of UV-irradiated cholera phage e5 in Vibrio cholerae MAK757.紫外线照射的霍乱噬菌体e5在霍乱弧菌MAK757中的可诱导再激活
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Ability of Bacillus subtilis protoplasts to repair irradiated bacteriophage deoxyribonucleic acid via acquired and natural enzymatic systems.枯草芽孢杆菌原生质体通过获得性和天然酶系统修复辐照噬菌体脱氧核糖核酸的能力。
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Neisseria gonorrhoeae 3. Demonstration of presumed appendages to cells from different colony types.淋病奈瑟菌 3. 不同菌落类型细胞上假定附属物的展示。
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Genetic transformation of Neisseria gonorrhoeae to streptomycin resistance.淋病奈瑟菌向链霉素抗性的遗传转化。
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Enzymatic synthesis of deoxyribonucleic acid. XXXII. Replication of duplex deoxyribonucleic acid by polymerase at a single strand break.脱氧核糖核酸的酶促合成。XXXII. 聚合酶在单链断裂处对双链脱氧核糖核酸的复制。
J Biol Chem. 1970 Jan 10;245(1):39-45.
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Endonuclease from Micrococcus luteus which has activity toward ultraviolet-irradiated deoxyribonucleic acid: purification and properties.来自藤黄微球菌的对紫外线照射的脱氧核糖核酸具有活性的核酸内切酶:纯化及性质
J Bacteriol. 1970 Apr;102(1):178-86. doi: 10.1128/jb.102.1.178-186.1970.
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Search for thymidine phosphorylase, nucleoside deoxyribosyltransferase and thymidine kinase in genus Neisseria.
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Postirradiation recovery dependent on the uvr-1 locus in Bacillus subtilis.枯草芽孢杆菌中依赖uvr-1位点的辐照后恢复。
J Bacteriol. 1976 Oct;128(1):317-24. doi: 10.1128/jb.128.1.317-324.1976.