淋病奈瑟菌的DNA切除修复系统。
A DNA excision repair system for Neisseria gonorrhoeae.
作者信息
Campbell L A, Yasbin R E
出版信息
Mol Gen Genet. 1984;193(3):561-3. doi: 10.1007/BF00382101.
PMID:6423936
Abstract
The removal of pyrimidine dimers from deoxyribonucleic acid of ultraviolet irradiated cultures of Neisseria gonorrhoeae can not be readily ascertained by using radioactively labeled thymidine precursors. However, by adapting the alkaline agarose gel technique of Achey et al. (Photochem Photobiol 29, 305-310, 1979), it was possible to demonstrate that this human pathogen does possess an active excision repair system that functions on pyrimidine dimers.
摘要
利用放射性标记的胸腺嘧啶核苷前体，无法轻易确定从经紫外线照射的淋病奈瑟菌培养物的脱氧核糖核酸中去除嘧啶二聚体的情况。然而，通过采用阿奇等人（《光化学与光生物学》29卷，305 - 310页，1979年）的碱性琼脂糖凝胶技术，有可能证明这种人类病原体确实拥有一个作用于嘧啶二聚体的活性切除修复系统。
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