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[人中性粒细胞对白喉棒状杆菌肽聚糖的直接IgG介导反应性]

[Direct IgG-mediated reactivity of human neutrophils to Corynebacterium diphtheriae peptidoglycan].

作者信息

Maianskiĭ A N, Shmeleva E A, Krylova N I, Maianskaia I V, Boiarinova L V

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1984 Feb(2):99-101.

PMID:6424364
Abstract

The direct and IgG-mediated reactivity to C. diphtheriae peptidoglycan in the system of neutrophilic phagocytosis was studied. Peptidoglycan treated with IgG (2-20 mg/ml) isolated from commercial immunoglobulin stimulated the reduction of nitro blue tetrazolium by human neutrophils. Direct (IgG-independent) reactions were much less intensive. The problem of normal IgG opsonizing C. diphtheriae peptidoglycan is discussed.

摘要

研究了嗜中性粒细胞吞噬系统中对白喉棒状杆菌肽聚糖的直接反应和IgG介导的反应。用从商业免疫球蛋白中分离出的IgG(2-20mg/ml)处理的肽聚糖刺激人中性粒细胞还原硝基蓝四氮唑。直接(不依赖IgG)反应强度要小得多。讨论了正常IgG调理白喉棒状杆菌肽聚糖的问题。

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