Jelley D M, Nicoll A G
Br Med J (Clin Res Ed). 1984 May 26;288(6430):1582-4. doi: 10.1136/bmj.288.6430.1582.
The immunisation records of 584 children who were born between 1978 and 1982, in a general practice of average social class distribution, were examined: 3.5% of the children would have been excluded from starting a course of vaccination including pertussis using contra-indications established by the Department of Health and Social Security. A further 3.5% had reactions to immunisation that were judged severe enough to prevent completing the course of vaccination. In 1981 and 1982 13% of parents refused pertussis vaccination, considerably fewer than from 1978 to 80. Concomitantly, immunisation against pertussis rose from 51% to 84% over the five year period. Given the incidence of contra-indications and the level of parental refusal, it is concluded that a pertussis uptake of 80% would be a reasonable target for any population.
对在一个社会阶层分布平均的普通诊所出生于1978年至1982年的584名儿童的免疫记录进行了检查:按照卫生和社会保障部制定的禁忌症,3.5%的儿童会被排除在开始包括百日咳在内的疫苗接种疗程之外。另有3.5%的儿童出现了被判定严重到足以阻止完成疫苗接种疗程的免疫反应。在1981年和1982年,13%的家长拒绝百日咳疫苗接种,比1978年至1980年要少得多。与此同时,在这五年期间,百日咳疫苗接种率从51%上升到了84%。考虑到禁忌症的发生率和家长拒绝的程度,得出结论:80%的百日咳疫苗接种率对任何人群来说都是一个合理的目标。