与食用啤酒酵母相关的假性卟啉症。
Pseudoporphyria associated with consumption of brewers' yeast.
作者信息
Lim C K, Rideout J M, Peters T J
出版信息
Br Med J (Clin Res Ed). 1984 Jun 2;288(6431):1640-2. doi: 10.1136/bmj.288.6431.1640.
A case of pseudoporphyria associated with excessive consumption of brewers ' yeast was studied. Detailed analysis of the yeast tablets by high performance liquid chromatography showed the presence of dicarboxylic deuteroporphyrin , mesoporphyrin, and protoporphyrin; coproporphyrin I and III isomers; and uroporphyrin I and III isomers. The faecal porphyrin concentration of the patient taking yeast tablets was significantly increased, resembling the excretion pattern in variegate porphyria. Any patient showing an unusual porphyrin excretion pattern on high performance liquid chromatography should be investigated for a possible dietary cause.
研究了一例与过量食用啤酒酵母相关的假性卟啉症病例。通过高效液相色谱对酵母片进行详细分析，结果显示存在二羧酸原卟啉、中卟啉和原卟啉；粪卟啉I和III异构体；以及尿卟啉I和III异构体。服用酵母片患者的粪便卟啉浓度显著升高，类似于杂合性卟啉症的排泄模式。任何在高效液相色谱上显示异常卟啉排泄模式的患者都应调查是否存在可能的饮食原因。
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