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Human pulmonary alveolar macrophages metabolise benzo(a)pyrene to proximate and ultimate mutagens.

作者信息

Harris C C, Hsu I C, Stoner G D, Trump B F, Selkirk J K

出版信息

Nature. 1978 Apr 13;272(5654):633-4. doi: 10.1038/272633a0.

DOI:10.1038/272633a0
PMID:643056
Abstract
摘要

相似文献

1
Human pulmonary alveolar macrophages metabolise benzo(a)pyrene to proximate and ultimate mutagens.人类肺泡巨噬细胞将苯并(a)芘代谢为近致癌物和终致癌物。
Nature. 1978 Apr 13;272(5654):633-4. doi: 10.1038/272633a0.
2
Uptake of benzo[a]pyrene--ferric oxide particulates by human pulmonary macrophages and release of benzo[a]pyrene and its metabolites.人肺巨噬细胞对苯并[a]芘 - 氧化铁颗粒的摄取以及苯并[a]芘及其代谢产物的释放。
Proc Soc Exp Biol Med. 1979 Jul;161(3):280-4. doi: 10.3181/00379727-161-40536.
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Patterns of benzo[alpha]pyrene metabolism in normal human pulmonary alveolar macrophages.正常人肺泡巨噬细胞中苯并[a]芘的代谢模式
Cancer Lett. 1979 Dec;8(2):103-9. doi: 10.1016/0304-3835(79)90002-8.
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Metabolism of [3H]benzo[a]pyrene by cultured human bronchus and cultured human pulmonary alveolar macrophages.培养的人支气管和培养的人肺泡巨噬细胞对[3H]苯并[a]芘的代谢
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[Studies on the metabolism of benzo(a)pyren in alveolar-macrophages. I. Uptake of benzo(a)pyrene and induction of benzo(a)pyrene hydroxylase (author's transl)].肺泡巨噬细胞中苯并(a)芘代谢的研究。I. 苯并(a)芘的摄取及苯并(a)芘羟化酶的诱导（作者译）
Zentralbl Bakteriol Orig B. 1975 May;160(3):191-211.
6
[Studies on the metabolism of benzo(a)pyrene in alveolar-macrophages. II. Kinetics of metabolism and characterization of the metabolites (author's transl)].[肺泡巨噬细胞中苯并(a)芘代谢的研究。II. 代谢动力学及代谢产物的特性（作者译）]
Zentralbl Bakteriol Orig B. 1975 Sep;161(1):1-25.
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Xenobiotic metabolism by alveolar type II cells isolated from rabbit lung.
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Induction of ouabain-resistant mutation and sister chromatid exchanges in Chinese hamster cells with chemical carcinogens mediated by human pulmonary macrophages.人肺巨噬细胞介导的化学致癌物诱导中国仓鼠细胞中哇巴因抗性突变和姐妹染色单体交换
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Metabolic inactivation of mutagenic benzo(a)pyrene metabolites: significance to carcinogenicity and implications for in vitro tests.诱变苯并(a)芘代谢物的代谢失活：对致癌性的意义及对体外试验的影响
Dev Toxicol Environ Sci. 1980;8:181-6.
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Comparative benzo[a]pyrene metabolite patterns in fish and rodents.鱼类和啮齿动物中苯并[a]芘代谢物模式的比较
Natl Cancer Inst Monogr. 1984 May;65:387-90.

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Environ Health Perspect. 1993 Mar;99:249-52. doi: 10.1289/ehp.9399249.
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Metabolic activation and lung toxicity: a basis for cell-selective pulmonary damage by foreign chemicals.代谢活化与肺毒性：外源化学物质导致细胞选择性肺损伤的基础。
Environ Health Perspect. 1984 Apr;55:47-51. doi: 10.1289/ehp.845547.
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Feasibility of route extrapolation in risk assessment.风险评估中途径外推的可行性。
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Organ specific metabolic activation of five extracts of indoor and outdoor particulate matter.室内和室外颗粒物五种提取物的器官特异性代谢活化
Arch Toxicol. 1988 Jan;61(3):213-7. doi: 10.1007/BF00316636.
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In vitro cytotoxicity of chrysotile asbestos to human pulmonary alveolar macrophages is decreased by organosilane coating and surfactant.有机硅烷涂层和表面活性剂可降低温石棉对人肺泡巨噬细胞的体外细胞毒性。
Cell Biol Toxicol. 1986 Jun;2(2):293-309. doi: 10.1007/BF00122697.
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