胃浆细胞瘤与多系统自身免疫性疾病

Gastric plasmacytoma and multisystem autoimmune disease.

作者信息

Nasu M, Matsubara O, Kamiyama R, Yamada T, Nishido T, Yamato H

出版信息

Virchows Arch A Pathol Anat Histopathol. 1984;404(1):109-15. doi: 10.1007/BF00704256.

Abstract

A 54-year-old women with solitary gastric plasmacytoma, Ig M and kappa-light chain type, associated with multisystem autoimmune disease is described. The gastric plasmacytoma developed seven years after the diagnosis of Hashimoto's thyroiditis, primary biliary cirrhosis and Sjögren's syndrome. We speculate that this plasmacytoma developed in association with an immunodeficient and/or immunosuppressed state resulting from multisystem autoimmune disease and therapy.

摘要

本文描述了一名54岁女性，患有IgM和κ轻链型孤立性胃浆细胞瘤，并伴有多系统自身免疫性疾病。胃浆细胞瘤在诊断为桥本甲状腺炎、原发性胆汁性肝硬化和干燥综合征7年后出现。我们推测，这种浆细胞瘤是在多系统自身免疫性疾病和治疗导致的免疫缺陷和/或免疫抑制状态下发生的。