Szerlip H M, Singer I
Am J Med. 1984 Sep;77(3):581-2. doi: 10.1016/0002-9343(84)90127-x.
Chlorine gas inhalation is usually accompanied by pulmonary toxicity and hypoxemia; the associated acidemia, when present, has been attributed to lactic acidosis. This case report describes the development of hyperchloremic metabolic acidosis following accidental chlorine gas exposure. The mechanism postulated for the production of this acidosis is the absorption of hydrochloric acid following the reaction of chlorine gas with tissue water. This may be the first case of chlorine toxicity in which the mechanism of the acidosis has been determined.
吸入氯气通常伴有肺毒性和低氧血症;若存在相关的酸血症,则归因于乳酸酸中毒。本病例报告描述了意外接触氯气后发生高氯性代谢性酸中毒的情况。推测这种酸中毒产生的机制是氯气与组织中的水反应后盐酸被吸收。这可能是首例已确定酸中毒机制的氯气中毒病例。