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多氯联苯:对出生体重和妊娠期的影响。

Polychlorinated biphenyls: influence on birthweight and gestation.

作者信息

Taylor P R, Lawrence C E, Hwang H L, Paulson A S

出版信息

Am J Public Health. 1984 Oct;74(10):1153-4. doi: 10.2105/ajph.74.10.1153.

Abstract

Fifty-one infants born to women employed at two capacitor manufacturing facilities with a history of high exposure to polychlorinated biphenyls (PCBs) had a mean birthweight of 153 grams less than that of 337 infants born to women who had worked in low-exposure areas (90 per cent confidence interval, -286 to -20 g); mean gestational age was 6.6 days shorter in the high-exposure infants (90 per cent CI, -10.3 to -2.9 days). After adjusting for gestational age, the difference in birthweight was markedly reduced, indicating that the observed reduction in birthweight was due mainly to shortening of gestational age in the high-exposure group.

摘要

在两家曾有高浓度多氯联苯(PCBs)暴露史的电容器制造工厂工作的女性所生的51名婴儿,其平均出生体重比在低暴露区工作的女性所生的337名婴儿轻153克(90%置信区间为-286至-20克);高暴露组婴儿的平均孕周比低暴露组婴儿短6.6天(90%置信区间为-10.3至-2.9天)。在对孕周进行校正后,出生体重的差异显著减小,这表明观察到的出生体重降低主要是由于高暴露组的孕周缩短所致。

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