Grubb B R, Bentley P J
Exp Eye Res. 1984 Jul;39(1):107-12. doi: 10.1016/0014-4835(84)90119-2.
Rabbit lenses incubated in a Ca-free medium gain Na and lose K, but this effect is reduced by the presence of strontium. Little Sr enters the lens under in vitro conditions and that which is present does not appear to significantly enter the lenticular cells. The Sr present, however, appears to be displaced by lanthanum, suggesting that Sr is interacting with the cell surface. This outer 'bound' Sr does not interfere with exchanges of Ca across the cell membrane but it may contribute to the control of lens permeability to Na and K. Uptake of Sr can be enhanced by exposure of the lens to a Ca-free medium or the Ca-Mg ionophore A23187.
在无钙培养基中孵育的兔晶状体摄取钠并丢失钾，但锶的存在会减弱这种效应。在体外条件下，很少有锶进入晶状体，而且晶状体中已有的锶似乎不会大量进入晶状体细胞。然而，已有的锶似乎会被镧取代，这表明锶正在与细胞表面相互作用。这种外部“结合”的锶不会干扰钙跨细胞膜的交换，但它可能有助于控制晶状体对钠和钾的通透性。将晶状体暴露于无钙培养基或钙-镁离子载体A23187中可增强锶的摄取。
