花生四烯酸的释放：补体晚期成分的一项新功能。
Release of arachidonic acid: a new function of the late complement components.
作者信息
Betz M, Hänsch G M
出版信息
Immunobiology. 1984 May;166(4-5):473-83. doi: 10.1016/S0171-2985(84)80024-8.
PMID:6434404
Abstract
Incubation of Ehrlich-ascites cells with sublytic complement doses results in degradation of membrane phospholipids and release of arachidonic acid. Phospholipase A2 blockers inhibit arachidonic acid release indicating a phospholipase dependent cleavage of the phospholipids. Phospholipase A2 is apparently activated during complement-membrane interaction, representing a new reactivity of the late complement components.
摘要
用亚溶细胞剂量的补体孵育艾氏腹水细胞会导致膜磷脂降解并释放花生四烯酸。磷脂酶A2阻滞剂可抑制花生四烯酸释放，表明磷脂的裂解依赖于磷脂酶。磷脂酶A2显然在补体与膜相互作用期间被激活，这代表了补体晚期成分的一种新反应性。
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