Labro M T, Perianin A, Kahn M F
Clin Rheumatol. 1984 Dec;3(4):435-41. doi: 10.1007/BF02031265.
The occurrence of antilymphocyte antibodies (AL-Ab) was investigated in the sera of 28 patients with scleroderma. By indirect immunofluorescence, we found these Ab in 53% of the sera. Inhibition of E rosette formation and lymphocytotoxicity revealed these Ab in 42% and 14% of the sera respectively. Most of the Ab (93%) reacted at 0 degrees C. These AL-Ab can be separated into several groups depending on their inhibitory activity on the lymphocyte membrane. In some cases, the receptor seems similar to that of sheep red blood cells. The study of the clinical features of the patients showed few differences between the groups with and those without Al-Ab. It must be noted that all the patients with the CREST syndrome (6 cases) possessed Al-Ab.
对28例硬皮病患者血清中的抗淋巴细胞抗体（AL-Ab）进行了研究。通过间接免疫荧光法，我们在53%的血清中发现了这些抗体。E玫瑰花结形成抑制试验和淋巴细胞毒性试验分别在42%和14%的血清中发现了这些抗体。大多数抗体（93%）在0℃时发生反应。这些抗淋巴细胞抗体可根据其对淋巴细胞膜的抑制活性分为几组。在某些情况下，其受体似乎与绵羊红细胞的受体相似。对患者临床特征的研究表明，有抗淋巴细胞抗体组和无抗淋巴细胞抗体组之间差异不大。必须指出的是，所有CREST综合征患者（6例）均有抗淋巴细胞抗体。
