卡介苗预处理对T细胞针对组织相容性抗原反应的抑制作用。
Suppression of T-cell responses to histocompatibility antigens by BCG pre-treatment.
作者信息
Orbach-Arbouys S, Castes M
出版信息
Immunology. 1980 Feb;39(2):263-8.
Abstract
The injection of 3 mg BCG into C57Bl/6 mice was followed 14 days later by a decrease in reactivity of spleen cells when engaged in mixed-lymphocyte reactions or in graft-versus-host reactions. In vitro, the lack of reactivity was due to an active suppression exerted mainly by the adherent population. In vivo, it was not possible to demonstrate active suppression.
摘要
给C57Bl/6小鼠注射3毫克卡介苗后14天，当脾细胞参与混合淋巴细胞反应或移植物抗宿主反应时，其反应性降低。在体外，反应性缺乏是由于主要由黏附细胞群体施加的主动抑制作用。在体内，无法证明存在主动抑制作用。
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