人淋巴细胞混合淋巴细胞培养与植物血凝素刺激反应之间的相关性。
Correlation between mixed lymphocyte culture and phytohaemagglutinin stimulation responses of human lymphocytes.
作者信息
Nanra S K, Boettcher B
出版信息
Clin Exp Immunol. 1980 Jul;41(1):173-5.
Abstract
In fifty-seven healthy individuals a significant correlation ( r = 0.3, P < 0.05) has been found between responses of their lymphocytes to stimulation by PHA and by pooled lymphocytes in MLC. It is suggested that these tests quantitate the general status of T cell reactivity of individuals, and may be used in conjunction with the results of other tests for T cell parameters, in a transplant programme to predict favourable outcome and to monitor immunosuppressive therapy.
摘要
在57名健康个体中，已发现其淋巴细胞对PHA刺激的反应与对混合淋巴细胞培养（MLC）中淋巴细胞刺激的反应之间存在显著相关性（r = 0.3，P < 0.05）。有人提出，这些检测可量化个体T细胞反应性的总体状态，并可在移植计划中与其他T细胞参数检测结果结合使用，以预测良好结局并监测免疫抑制治疗。
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本文引用的文献
1
Activation of human T and B lymphocytes by polyclonal mitogens.多克隆有丝分裂原对人T淋巴细胞和B淋巴细胞的激活作用。
Nature. 1974 Apr 19;248(5450):698-701. doi: 10.1038/248698a0.
2
A rapid micro-method for the phytohaemagglutinin-induced human lymphocyte transformation test.一种用于植物血凝素诱导的人淋巴细胞转化试验的快速微量方法。
Clin Exp Immunol. 1974 Sep;18(1):155-67.
3
Synergy between human T and B lymphocytes in their response to phythaemagglutinin and pokeweed mitogen.人T淋巴细胞和B淋巴细胞在对植物血凝素和商陆有丝分裂原反应中的协同作用。
Immunology. 1976 Aug;31(2):273-81.
4
Quantitation of pretransplantation immune responsiveness by in vitro T-cell testing.通过体外T细胞检测对移植前免疫反应性进行定量分析。
Transplant Proc. 1977 Mar;9(1):49-53.
5
Mixed-lymphocyte culture response in a related and an unrelated Australian population.
Med J Aust. 1979 Nov 17;2(10):518-21. doi: 10.5694/j.1326-5377.1979.tb127143.x.
6
Correlation of MLC response with graft survival in cadaver and related donor kidney transplants.尸体及相关供体肾移植中MLC反应与移植肾存活的相关性。
Transplant Proc. 1978 Dec;10(4):949-51.
7
Correlation between magnitude of MLC and kidney graft survival in intrafamilial transplantation.家族内移植中MLC强度与肾移植存活率的相关性。
Tissue Antigens. 1977 Nov;10(5):364-72. doi: 10.1111/j.1399-0039.1977.tb00772.x.
8
MLR-R and MLR-S gene products are expressed on different lymphoid cells.
Transplantation. 1977 Jul;24(1):63-9. doi: 10.1097/00007890-197707000-00009.
9
Significance of mixed leukocyte culture testing in cadaver kidney transplantation.混合白细胞培养试验在尸体肾移植中的意义
Transplantation. 1977 Apr;23(4):375-80. doi: 10.1097/00007890-197704000-00012.
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Transformation of lymphocytes from patients awaiting cadaver renal transplants.等待尸体肾移植患者淋巴细胞的转化
Lancet. 1976 Sep 11;2(7985):529-31. doi: 10.1016/s0140-6736(76)91790-6.
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