• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

粗糙脉孢菌细胞质中苯丙氨酸转运RNA的核苷酸序列。

The nucleotide sequence of phenylalanine tRNA from the cytoplasm of Neurospora crassa.

作者信息

Alzner-DeWeerd B, Hecker L I, Barnett W E, RajBhandary U L

出版信息

Nucleic Acids Res. 1980 Mar 11;8(5):1023-32. doi: 10.1093/nar/8.5.1023.

DOI:10.1093/nar/8.5.1023
PMID:6449691
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC323970/
Abstract

The phenylalanine tRNA from the cytoplasm of Neurospora crassa has been purified and sequenced. The sequence is: pGCGGGUUUAm2GCUCA (N) GDDGGGAGAGCm22GpsiCAGACmUGmAAYApsim5CUGAAGm7GDm5CGUGUGTpsiCGm1AUCCACACAAACCGCACCAOH. Both in the nature of modified nucleotides which are present in this tRNA and in the overall sequence, this tRNA resembles more closely phenylalanine tRNAs of eukaryotic cytoplasm than those of prokaryotes. The sequence of this tRNA differs from those of the corresponding tRNAs of wheat germ and yeast by only 6 and 7 nucleotides respectively out of 76 nucleotides.U

摘要

粗糙脉孢菌细胞质中的苯丙氨酸转运核糖核酸（tRNA）已被纯化并测序。其序列为：pGCGGGUUUAm2GCUCA（N）GDDGGGAGAGCm22GpsiCAGACmUGmAAYApsim5CUGAAGm7GDm5CGUGUGTpsiCGm1AUCCACACAAACCGCACCAOH。无论是在该tRNA中存在的修饰核苷酸的性质还是在整体序列方面，与原核生物的苯丙氨酸tRNA相比，这种tRNA与真核细胞质中的苯丙氨酸tRNA更为相似。在76个核苷酸中，这种tRNA的序列与小麦胚芽和酵母相应tRNA的序列分别仅相差6个和7个核苷酸。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1638/323970/1d8d71ae9b7d/nar00422-0107-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1638/323970/1d8d71ae9b7d/nar00422-0107-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1638/323970/1d8d71ae9b7d/nar00422-0107-a.jpg

相似文献

1
The nucleotide sequence of phenylalanine tRNA from the cytoplasm of Neurospora crassa.粗糙脉孢菌细胞质中苯丙氨酸转运RNA的核苷酸序列。
Nucleic Acids Res. 1980 Mar 11;8(5):1023-32. doi: 10.1093/nar/8.5.1023.
2
A phenylalanine tRNA gene from Neurospora crassa: conservation of secondary structure involving an intervening sequence.来自粗糙脉孢菌的苯丙氨酸转运RNA基因：涉及间隔序列的二级结构保守性
Nucleic Acids Res. 1980 Mar 11;8(5):1033-42. doi: 10.1093/nar/8.5.1033.
3
Novel features in the genetic code and codon reading patterns in Neurospora crassa mitochondria based on sequences of six mitochondrial tRNAs.基于六种线粒体tRNA序列的粗糙脉孢菌线粒体遗传密码和密码子阅读模式的新特征
Proc Natl Acad Sci U S A. 1980 Jun;77(6):3159-63. doi: 10.1073/pnas.77.6.3159.
4
Nucleotide sequence of Neurospora crassa cytoplasmic initiator tRNA.粗糙脉孢菌细胞质起始tRNA的核苷酸序列。
Nucleic Acids Res. 1977 Dec;4(12):4109-31. doi: 10.1093/nar/4.12.4109.
5
The Neurospora mitochondrial genome: the region coding for the polycistronic cytochrome oxidase subunit I transcript is preceded by a transfer RNA gene.粗糙脉孢菌线粒体基因组：编码多顺反子细胞色素氧化酶亚基I转录本的区域之前有一个转运RNA基因。
FEBS Lett. 1985 Jan 7;179(2):337-42. doi: 10.1016/0014-5793(85)80547-0.
6
Interesting and unusual features in the sequence of Neurospora crassa mitochondrial tyrosine transfer RNA.粗糙脉孢菌线粒体酪氨酸转移核糖核酸序列中的有趣且不寻常的特征。
Proc Natl Acad Sci U S A. 1979 Feb;76(2):717-21. doi: 10.1073/pnas.76.2.717.
7
Nucleotide sequence of a spinach chloroplast valine tRNA.菠菜叶绿体缬氨酸转运核糖核酸的核苷酸序列。
Nucleic Acids Res. 1981 Jun 11;9(11):2543-7. doi: 10.1093/nar/9.11.2543.
8
Accurate transcription of homologous 5S rRNA and tRNA genes and splicing of tRNA in vitro by soluble extracts of Neurospora.脉孢菌可溶性提取物在体外对同源5S rRNA和tRNA基因的准确转录及tRNA的剪接
Nucleic Acids Res. 1984 Jul 25;12(14):5737-55. doi: 10.1093/nar/12.14.5737.
9
The nucleotide sequences of the initiator transfer RNAs from bean cytoplasm and chloroplasts.来自菜豆细胞质和叶绿体的起始转运核糖核酸的核苷酸序列。
Nucleic Acids Res. 1980 Mar 11;8(5):999-1008. doi: 10.1093/nar/8.5.999.
10
Characterization of an unusual tRNA-like sequence found inserted in a Neurospora retroplasmid.在粗糙脉孢菌逆转录质粒中发现的一种不寻常的类tRNA序列的特征分析。
Nucleic Acids Res. 2000 Jul 1;28(13):1514-24. doi: 10.1093/oxfordjournals.nar.a027018.

引用本文的文献

1
Direct Sequencing of tRNA by 2D-HELS-AA MS Seq Reveals Its Different Isoforms and Dynamic Base Modifications.二维 HELS-AA MS Seq 直接测序 tRNA 揭示其不同的同工型和动态碱基修饰。
ACS Chem Biol. 2020 Jun 19;15(6):1464-1472. doi: 10.1021/acschembio.0c00119. Epub 2020 May 19.
2
A phenylalanine tRNA gene from Neurospora crassa: conservation of secondary structure involving an intervening sequence.来自粗糙脉孢菌的苯丙氨酸转运RNA基因：涉及间隔序列的二级结构保守性
Nucleic Acids Res. 1980 Mar 11;8(5):1033-42. doi: 10.1093/nar/8.5.1033.
3
Compilation of tRNA sequences and sequences of tRNA genes.

本文引用的文献

1
A phenylalanine tRNA gene from Neurospora crassa: conservation of secondary structure involving an intervening sequence.来自粗糙脉孢菌的苯丙氨酸转运RNA基因：涉及间隔序列的二级结构保守性
Nucleic Acids Res. 1980 Mar 11;8(5):1033-42. doi: 10.1093/nar/8.5.1033.
2
Studies on polynucleotides. LXXIX. Yeast phenylalanine transfer ribonucleic acid: products obtained by degradation with pancreatic ribonuclease.多核苷酸研究。第七十九篇。酵母苯丙氨酸转移核糖核酸：用胰核糖核酸酶降解得到的产物
J Biol Chem. 1968 Feb 10;243(3):575-83.
3
Structure of the fluorescent Y base from yeast phenylalanine transfer ribonucleic acid.
tRNA序列及tRNA基因序列的汇编。
Nucleic Acids Res. 1991 Apr 25;19 Suppl(Suppl):2127-71. doi: 10.1093/nar/19.suppl.2127.
来自酵母苯丙氨酸转移核糖核酸的荧光Y碱基的结构。
J Am Chem Soc. 1970 Dec 30;92(26):7617-9. doi: 10.1021/ja00729a035.
4
A two-dimensional fractionation procedure for radioactive nucleotides.一种用于放射性核苷酸的二维分级分离程序。
J Mol Biol. 1965 Sep;13(2):373-98. doi: 10.1016/s0022-2836(65)80104-8.
5
Use of DNA polymerase I primed by a synthetic oligonucleotide to determine a nucleotide sequence in phage fl DNA.使用由合成寡核苷酸引发的DNA聚合酶I来确定噬菌体f1 DNA中的核苷酸序列。
Proc Natl Acad Sci U S A. 1973 Apr;70(4):1209-13. doi: 10.1073/pnas.70.4.1209.
6
Absence of the sequence G-T-psi-C-G(A)- in several eukaryotic cytoplasmic initiator transfer RNAs.几种真核细胞质起始转运核糖核酸中不存在G-T-假尿嘧啶-C-G(A)序列。
Proc Natl Acad Sci U S A. 1973 Apr;70(4):1041-5. doi: 10.1073/pnas.70.4.1041.
7
Replacement of the sequence G-T-phi-C-G(A)- by G-A-U-C-G- in initiator transfer RNA of rabbit-liver cytoplasm.兔肝细胞质起始转运核糖核酸中G-T-φ-C-G(A)序列被G-A-U-C-G-取代。
Proc Natl Acad Sci U S A. 1973 Sep;70(9):2600-4. doi: 10.1073/pnas.70.9.2600.
8
Nucleotide sequence of salmon testes and salmon liver cytoplasmic initiator tRNA.鲑鱼睾丸和鲑鱼肝脏细胞质起始tRNA的核苷酸序列。
Cell. 1975 Nov;6(3):395-405. doi: 10.1016/0092-8674(75)90189-0.
9
The first nucleotide sequence of an organelle transfer RNA: chloroplastic tRNAphe.细胞器转移RNA的首个核苷酸序列：叶绿体苯丙氨酸tRNA
Cell. 1976 Dec;9(4 PT 2):717-23. doi: 10.1016/0092-8674(76)90135-5.
10
Primary structure of bean chloroplastic tRNAPhe. Comparison with Euglena chloroplastic tRNAPhe.菜豆叶绿体苯丙氨酸转运RNA的一级结构。与眼虫叶绿体苯丙氨酸转运RNA的比较。
FEBS Lett. 1977 Dec 15;84(2):351-6. doi: 10.1016/0014-5793(77)80723-0.