Olsen M, Pettersson H, Kiessling K H
Acta Pharmacol Toxicol (Copenh). 1981 Feb;48(2):157-61. doi: 10.1111/j.1600-0773.1981.tb01602.x.
The distribution of the zearalenone reducing activity was investigated in liver fractions obtained by differential centrifugation of liver homogenate from adult female Sprague Dawley rats. The zearalenone reducing enzyme was identified as 3 alpha-hydroxysteroid dehydrogenase. At least two multiple forms occur of the enzyme with different subcellular locations and pH-optima. The activity was localized in the microsomes with NADH as coenzyme and in both microsomes and cytosol with NADPH.
通过对成年雌性斯普拉格-道利大鼠肝脏匀浆进行差速离心获得肝脏组分，研究了玉米赤霉烯酮还原活性的分布。玉米赤霉烯酮还原酶被鉴定为3α-羟基类固醇脱氢酶。该酶至少存在两种多种形式，具有不同的亚细胞定位和最适pH值。以NADH为辅酶时，活性定位于微粒体；以NADPH为辅酶时，活性定位于微粒体和胞质溶胶。
