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新生儿坏死性小肠结肠炎中免疫复合物性血管炎的证据。

Evidence for an immune complex vasculitis in neonatal necrotising enterocolitis.

作者信息

Gray E S, Lloyd D J, Miller S S, Davidson A I, Balch N J, Horne C H

出版信息

J Clin Pathol. 1981 Jul;34(7):759-63. doi: 10.1136/jcp.34.7.759.

DOI:10.1136/jcp.34.7.759
PMID:6455447
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC493807/
Abstract

Despite many attractive hypotheses, neonatal necrotising enterocolitis (NNEC) remains a disease of unknown aetiology. By means of the immunofluorescent direct sandwich technique we have demonstrated immune complex deposition in the small vessels of the diseased bowel wall. We believe this is the first report of evidence of an immunological reaction occurring in this disease.

摘要

尽管有许多引人注目的假说，但新生儿坏死性小肠结肠炎（NNEC）的病因仍然不明。通过免疫荧光直接夹心技术，我们已经证实在患病肠壁的小血管中有免疫复合物沉积。我们认为这是关于该疾病中发生免疫反应证据的首次报道。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abad/493807/a312f7723416/jclinpath00488-0068-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abad/493807/8700de8fe4fa/jclinpath00488-0066-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abad/493807/119bcc98830b/jclinpath00488-0067-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abad/493807/56de58666b8e/jclinpath00488-0067-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abad/493807/a312f7723416/jclinpath00488-0068-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abad/493807/8700de8fe4fa/jclinpath00488-0066-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abad/493807/119bcc98830b/jclinpath00488-0067-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abad/493807/56de58666b8e/jclinpath00488-0067-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abad/493807/a312f7723416/jclinpath00488-0068-a.jpg

相似文献

1
Evidence for an immune complex vasculitis in neonatal necrotising enterocolitis.新生儿坏死性小肠结肠炎中免疫复合物性血管炎的证据。
J Clin Pathol. 1981 Jul;34(7):759-63. doi: 10.1136/jcp.34.7.759.
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引用本文的文献

1
[Not Available].[无可用内容]。
Ann Inst Pasteur Microbiol. 1986 Jul 8;137(1):61-75. doi: 10.1016/S0769-2609(86)80094-1. Epub 2007 Aug 26.
2
Role of the Schwartzmann reaction in necrotising enterocolitis.施瓦茨曼反应在坏死性小肠结肠炎中的作用。
J Clin Pathol. 1981 Dec;34(12):1405-6. doi: 10.1136/jcp.34.12.1405-b.
3
Group B streptococcal serotypes correlated with maternal parity and carrier sites.B族链球菌血清型与产妇胎次及携带部位相关。

本文引用的文献

1
PERFORATION OF THE COLON FROM NECROTIZING COLITIS IN THE NEWBORN: REPORT OF A SURVIVAL AND A NEW ETIOLOGIC CONCEPT.新生儿坏死性结肠炎所致结肠穿孔：一例存活报告及新的病因学概念
Surgery. 1965 Aug;58:436-41.
2
NECROTIZING ENTEROCOLITIS IN PREMATURE INFANTS.早产儿坏死性小肠结肠炎
J Pediatr. 1965 Apr;66:697-705. doi: 10.1016/s0022-3476(65)80003-8.
3
The Arthus phenomenon in the colon of rabbits; a serial histological study.兔结肠中的阿瑟斯现象；一项系列组织学研究。
J Clin Pathol. 1981 Dec;34(12):1405. doi: 10.1136/jcp.34.12.1405-a.
4
Experimental model of ischemic bowel necrosis. The role of platelet-activating factor and endotoxin.缺血性肠坏死的实验模型。血小板活化因子和内毒素的作用。
Am J Pathol. 1983 Jul;112(1):127-35.
AMA Arch Pathol. 1959 May;67(5):556-71.
4
The etiology of gastrointestinal perforations in the newborn.
J Pediatr Surg. 1969 Feb;4(1):77-84. doi: 10.1016/0022-3468(69)90186-9.
5
Intestinal perforation, exchange transfusion, and P.V.C.
Lancet. 1969 Dec 6;2(7632):1246. doi: 10.1016/s0140-6736(69)90770-3.
6
Uptake and transport of macromolecules by the intestine. Possible role in clinical disorders.肠道对大分子的摄取与转运。在临床疾病中的可能作用。
Gastroenterology. 1974 Sep;67(3):531-50.
7
Hyperviscosity syndrome associated with necrotizing enterocolitis.与坏死性小肠结肠炎相关的高黏滞综合征
Am J Dis Child. 1975 Oct;129(10):1192-4. doi: 10.1001/archpedi.1975.02120470042011.
8
Development of the capacity to produce specific antibody to an ingested food antigen in the premature infant.早产儿产生针对摄入食物抗原的特异性抗体能力的发展。
J Pediatr. 1975 Oct;87(4):515-8. doi: 10.1016/s0022-3476(75)80811-0.
9
Neonatal necrotizing enterocolitis: a disease of altered host defense.新生儿坏死性小肠结肠炎：一种宿主防御功能改变的疾病。
Clin Gastroenterol. 1977 May;6(2):463-80.
10
Neonatal necrotising enterocolitis.
J Clin Pathol. 1979 Nov;32(11):1090-9. doi: 10.1136/jcp.32.11.1090.