新生儿坏死性小肠结肠炎中免疫复合物性血管炎的证据。
Evidence for an immune complex vasculitis in neonatal necrotising enterocolitis.
作者信息
Gray E S, Lloyd D J, Miller S S, Davidson A I, Balch N J, Horne C H
出版信息
J Clin Pathol. 1981 Jul;34(7):759-63. doi: 10.1136/jcp.34.7.759.
Abstract
Despite many attractive hypotheses, neonatal necrotising enterocolitis (NNEC) remains a disease of unknown aetiology. By means of the immunofluorescent direct sandwich technique we have demonstrated immune complex deposition in the small vessels of the diseased bowel wall. We believe this is the first report of evidence of an immunological reaction occurring in this disease.
摘要
尽管有许多引人注目的假说，但新生儿坏死性小肠结肠炎（NNEC）的病因仍然不明。通过免疫荧光直接夹心技术，我们已经证实在患病肠壁的小血管中有免疫复合物沉积。我们认为这是关于该疾病中发生免疫反应证据的首次报道。
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