在儿童丘疹性肢端皮炎（詹诺蒂病）流行中检测乙型肝炎表面抗原adr亚型。
Detection of hepatitis B surface antigen subtype adr in an epidemic of papular acrodermatitis of childhood (Gianotti's disease).
作者信息
Kanzaki S, Kanda S, Terada K, Nohno S, Kumano K, Narahara K, Hayashi H, Kimoto H
出版信息
Acta Med Okayama. 1981 Dec;35(6):407-10. doi: 10.18926/AMO/31260.
Papular acrodermatitis of childhood (PAC) has recently been reported to be associated with hepatitis B surface antigen (HBsAg) subtype ayw. Between September, 1978, and June, 1979, we saw 14 patients with PAC in a small epidemic occurring in Iwakuni City, Japan. HBsAg was detected in sera from all patients. Subtyping of HBsAg in 11 patients showed that 8 had a determinant adr and 3 had no detectable determinant because of low antigen titers. The result suggests that factors other than the specific HBsAg subtype contribute to the development of PAC.
儿童丘疹性肢端皮炎（PAC）最近有报道称与乙型肝炎表面抗原（HBsAg）ayw亚型有关。1978年9月至1979年6月期间，我们在日本岩国市发生的一次小范围流行中诊治了14例PAC患者。所有患者血清中均检测到HBsAg。对11例患者的HBsAg进行亚型分型显示，8例有adr决定簇，3例因抗原滴度低未检测到决定簇。该结果表明，除特定的HBsAg亚型外，其他因素也与PAC的发生有关。
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