Riou F, Cespuglio R, Jouvet M
C R Seances Acad Sci III. 1981 Nov 30;293(12):679-82.
The intraventricular injection of 100 ng of vasoactive intestinal polypeptide (VIP) is followed by a significant increase of paradoxical sleep in the Rat. In P. chlorophenylalanine pretreated insomniac Rats which do not present spontaneous paradoxical sleep episodes, intraventricular injection of VIP induces normal quantities of this state of sleep.
向大鼠脑室内注射100纳克血管活性肠肽（VIP）后，其异相睡眠显著增加。在经对氯苯丙氨酸预处理的失眠大鼠中，这些大鼠原本不会出现自发性异相睡眠发作，而向其脑室内注射VIP后可诱导出正常量的这种睡眠状态。
