Spectinomycin is a broad-spectrum aminocyclitol antibiotic that is highly effective in the treatment of uncomplicated gonorrhea. It is the drug of choice for the treatment of gonorrhea that fails to respond to other therapy and is a good alternative drug in the treatment of penicillin-allergic patients. Spectinomycin should be considered the drug of choice in the treatment of gonorrhea in areas where penicillinase-producing strains of Neisseria gonorrhoeae are prevalent. Spectinomycin is not predictably effective in the treatment of oral pharyngeal gonorrhea but may be used in penicillin-allergic patients with disseminated gonorrhea. While spectinomycin has some activity against other human pathogens, it is unlikely that this agent will be found useful in infections other than those due to Neisseria gonorrhoeae.
壮观霉素是一种广谱氨基环醇类抗生素，对单纯性淋病的治疗非常有效。它是对其他治疗无反应的淋病治疗的首选药物，也是青霉素过敏患者治疗的良好替代药物。在产青霉素酶的淋病奈瑟菌流行的地区，壮观霉素应被视为淋病治疗的首选药物。壮观霉素对口咽部淋病的治疗效果不可预测，但可用于患有播散性淋病的青霉素过敏患者。虽然壮观霉素对其他人类病原体有一定活性，但除淋病奈瑟菌引起的感染外，不太可能在其他感染中发现该药物有用。
