Galatzer A, Beth-Halachmi N, Kauli R, Laron Z
Pediatrics. 1984 Aug;74(2):246-9.
The IQ of 52 girls with precocious puberty (mean age 9.5 +/- 2.8 years) was compared with that of 51 normal matched control subjects (mean age 9.7 +/- 2.8 years) and with that of eight girls with fast puberty (onset at normal age but accelerated advancement). Girls with precocious puberty had a significantly higher verbal IQ score than the control subjects but no difference was found in the performance score. The distribution of the verbal IQ score in the girls with precocious puberty was skewed toward the upper side of the theoretical distribution curve. The distribution was two or more times the expected theoretical percentile in the above average area (greater than 110, 56.9% v 25%), and five times more in the very superior area (greater than 130, 10.1% v 2.2%). The girls with fast puberty had the same behavior as the population with normal development. The results are interpreted as possible evidence of an effect of sex hormones on brain development, especially on the left hemisphere, during the prepubertal period.
对52名性早熟女孩（平均年龄9.5±2.8岁）的智商与51名年龄匹配的正常对照受试者（平均年龄9.7±2.8岁）以及8名青春期发育快（正常年龄开始但进展加速）的女孩的智商进行了比较。性早熟女孩的语言智商得分显著高于对照受试者，但操作智商得分未发现差异。性早熟女孩的语言智商得分分布向理论分布曲线的上侧倾斜。在高于平均水平的区域（大于110，56.9%对25%），该分布是预期理论百分位数的两倍或更多，在非常优秀的区域（大于130，10.1%对2.2%）则是五倍多。青春期发育快的女孩表现与正常发育人群相同。这些结果被解释为可能证明了青春期前性激素对大脑发育，尤其是对左半球发育产生影响的证据。
