• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

肺牵张感受器对家兔咳嗽反射的影响。

Influence of lung stretch receptors on the cough reflex in rabbits.

作者信息

Hanácek J, Davies A, Widdicombe J G

出版信息

Respiration. 1984;45(3):161-8. doi: 10.1159/000194614.

DOI:10.1159/000194614
PMID:6463386
Abstract

The cough reflex in anaesthetized rabbits was elicited by irritation of the larynx with ammonia, inhalation of ammonia into the lungs, and mechanical stimulation of the tracheobronchial tree with a catheter. After block of lung stretch receptors with sulphur dioxide and virtual abolition of the Breuer-Hering inflation reflex, the cough response to all three stimuli was far less frequent and, when it occurred, was weaker especially with respect to the expiratory efforts. It is concluded that the Breuer-Hering reflex enhances the cough reflex, although modification of the sensitivity of tracheobronchial cough and irritant receptors by sulphur dioxide may also influence the cough.

摘要

通过用氨刺激喉、将氨吸入肺以及用导管对气管支气管树进行机械刺激来引发麻醉兔的咳嗽反射。在用二氧化硫阻断肺牵张感受器并几乎消除布雷尔 - 黑林充气反射后,对所有三种刺激的咳嗽反应频率远低于之前,并且当咳嗽发生时,其强度较弱,尤其是呼气动作方面。得出的结论是,布雷尔 - 黑林反射增强了咳嗽反射,尽管二氧化硫对气管支气管咳嗽感受器和刺激感受器敏感性的改变也可能影响咳嗽。

相似文献

1
Influence of lung stretch receptors on the cough reflex in rabbits.肺牵张感受器对家兔咳嗽反射的影响。
Respiration. 1984;45(3):161-8. doi: 10.1159/000194614.
2
Airway receptors in cough.咳嗽中的气道感受器。
Bull Eur Physiopathol Respir. 1984 Jan-Feb;20(1):43-7.
3
Cough reflex in rabbits 24-h and 48-h after sulphur dioxide breathing.二氧化硫吸入后24小时和48小时家兔的咳嗽反射
Acta Physiol Hung. 1991;77(2):179-85.
4
The expiration reflex from the trachea and bronchi.来自气管和支气管的呼气反射。
Eur Respir J. 2008 Feb;31(2):385-90. doi: 10.1183/09031936.00063507. Epub 2007 Oct 24.
5
Lung reflexes in rabbits during pulmonary stretch receptor block by sulphur dioxide.二氧化硫阻断肺牵张感受器时家兔的肺反射
Respir Physiol. 1978 Jul;34(1):83-101. doi: 10.1016/0034-5687(78)90050-6.
6
[Function of pulmonary stretch receptors in defensive reflexes of the pulmonary system].[肺牵张感受器在肺系统防御反射中的作用]
Cesk Fysiol. 1981 May;30(3):247-9.
7
Provocation of aspiration reflexes and their effects on the pattern of cough and reflex apnea in cats.诱发咳嗽反射及其对猫咳嗽和反射性呼吸暂停模式的影响。
J Physiol Pharmacol. 2009 Nov;60 Suppl 5:99-104.
8
Lung C-fibre receptor activation and defensive reflexes in anaesthetized cats.麻醉猫的肺C纤维受体激活与防御反射
J Physiol. 1988 Aug;402:411-20. doi: 10.1113/jphysiol.1988.sp017212.
9
Influence of sulphur dioxide breathing on defensive reflexes of the airways.二氧化硫吸入对气道防御反射的影响。
Acta Physiol Hung. 1987;70(2-3):227-33.
10
Effects of hypercapnia on Breuer-Hering threshold for inspiratory termination.高碳酸血症对吸气终止的布雷尔-黑林阈值的影响。
J Appl Physiol Respir Environ Exerc Physiol. 1984 Oct;57(4):1211-21. doi: 10.1152/jappl.1984.57.4.1211.

引用本文的文献

1
A vagal-brainstem interoceptive circuit for cough-like defensive behaviors in mice.迷走神经-脑桥内脏感觉回路介导小鼠类咳嗽防御行为
Nat Neurosci. 2024 Sep;27(9):1734-1744. doi: 10.1038/s41593-024-01712-5. Epub 2024 Jul 8.
2
Identifying vagal bronchopulmonary afferents mediating cough response to inhaled sulfur dioxide in mice.鉴定介导小鼠吸入二氧化硫咳嗽反应的迷走支气管肺传入神经。
Am J Physiol Regul Integr Comp Physiol. 2024 Jul 1;327(1):R79-R87. doi: 10.1152/ajpregu.00281.2023. Epub 2024 May 20.
3
Inhibitory effect of sulfur dioxide inhalation on Hering-Breuer inflation reflex in mice: role of voltage-gated potassium channels.
二氧化硫吸入对小鼠 Hering-Breuer 充气反射的抑制作用:电压门控钾通道的作用。
J Appl Physiol (1985). 2023 May 1;134(5):1075-1082. doi: 10.1152/japplphysiol.00714.2022. Epub 2023 Mar 23.
4
Early exposure to farm dust in an allergic airway inflammation rabbit model: Does it affect bronchial and cough hyperresponsiveness?早期接触过敏性气道炎症兔模型中的农场灰尘:会影响支气管和咳嗽高反应性吗?
PLoS One. 2023 Jan 27;18(1):e0279498. doi: 10.1371/journal.pone.0279498. eCollection 2023.
5
Influence of intrathoracic vagotomy on the cough reflex in the anesthetized cat.胸腔内迷走神经切断术对麻醉猫咳嗽反射的影响。
Respir Physiol Neurobiol. 2022 Feb;296:103805. doi: 10.1016/j.resp.2021.103805. Epub 2021 Oct 19.
6
Differential effects of acute cerebellectomy on cough in spontaneously breathing cats.急性小脑切除术对自主呼吸猫咳嗽的差异影响。
PLoS One. 2021 Jun 21;16(6):e0253060. doi: 10.1371/journal.pone.0253060. eCollection 2021.
7
Strategies for the Integration of Cough and Swallow to Maintain Airway Protection in Humans.人类咳嗽与吞咽的整合策略以维持气道保护
Lung. 2018 Oct;196(5):601-608. doi: 10.1007/s00408-018-0133-7. Epub 2018 Jun 20.
8
Microinjection of kynurenic acid in the rostral nucleus of the tractus solitarius disrupts spatiotemporal aspects of mechanically induced tracheobronchial cough.向孤束核吻侧核微量注射犬尿氨酸会破坏机械诱导的气管支气管咳嗽的时空特征。
J Neurophysiol. 2017 Jun 1;117(6):2179-2187. doi: 10.1152/jn.00935.2016. Epub 2017 Mar 1.
9
Improved Cough and Cough-Specific Quality of Life in Patients Treated for Scleroderma-Related Interstitial Lung Disease: Results of Scleroderma Lung Study II.硬皮病相关间质性肺病患者咳嗽及咳嗽特异性生活质量改善:硬皮病肺部研究II的结果
Chest. 2017 Apr;151(4):813-820. doi: 10.1016/j.chest.2016.11.052. Epub 2016 Dec 22.
10
Vagal Afferent Innervation of the Airways in Health and Disease.健康与疾病状态下气道的迷走传入神经支配
Physiol Rev. 2016 Jul;96(3):975-1024. doi: 10.1152/physrev.00039.2015.