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皮肤原发性接种性结核。解剖者甲沟炎

Primary inoculation tuberculosis of the skin. Prosector's paronychia,

作者信息

Goette D K, Jacobson K W, Doty R D

出版信息

Arch Dermatol. 1978 Apr;114(4):567-9.

PMID:646369
Abstract

Subsequent to an autopsy of a tuberculotic cadaver, a pathology resident presented with a painless paronychia and axillary adenopathy after surgical incision and broad-spectrum antibiotics had failed to improve his condition. Demonstration by culture of Mycobacterium tuberculosis var hominis, positive smears, and findings of acid-fast organisms in a skin biopsy specimen proved the diagnosis of tuberculosis. Conversion of a previously negative skin test permitted the diagnosis of primary inoculation tuberculosis of the skin. The disease responded well to treatment with isoniazid, rifampin, and pyridoxine hydrochloride.

摘要

在对一名结核病患者尸体进行尸检后,一名病理学住院医师出现了无痛性甲沟炎和腋窝淋巴结病,此前手术切开并使用广谱抗生素治疗均未能改善其病情。结核分枝杆菌人型变种培养结果、涂片阳性以及皮肤活检标本中抗酸菌的发现证实了结核病的诊断。之前阴性的皮肤试验转为阳性,从而确诊为原发性皮肤接种结核病。该疾病对异烟肼、利福平和盐酸吡哆醇治疗反应良好。

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