Vuorenkoski V, Lenko H L, Tjernlund P, Vuorenkoski L, Perheentupa J
Arch Dis Child. 1978 Mar;53(3):201-9. doi: 10.1136/adc.53.3.201.
A simple treatment was shown to be suitable for clinical measurement of fundamental voice frequency. Basal frequency (SFF) and lowest frequency (LF) were determined in 374 normal subjects aged 6 years to adulthood. SFF fell between ages 8 and 10 years in boys (from 259 to 247 Hz), but not in girls (253 Hz). LF fell between ages 6 and 10 years in boys (from 234 to 203 Hz) and girls (from 230 to 218 Hz), and a sex difference appeared. In puberty, parallel to pubic hair (PH) development, a gradual fall of SFF and LF occurred in both boys (to 100 and 90 Hz, respectively) and girls (to 213 and 180 Hz). As a group, young hypopituitary children and girls with Turner's syndrome had a high SFF, and prepubertal boys with delayed maturation a low SFF. In some children with prenatal growth failure, SFF was abnormally high. The girls with Turner's syndrome exhibited a high, though individually variable, sensitivity of voice to androgen; their voices became lower before the appearance of any other masculinising effects. The instrument is useful for characterisation of growth failure syndromes and stages of puberty. It is particularly recommended for monitoring an undesirable effect on the voice during androgen treatment.
一种简单的治疗方法被证明适用于基本语音频率的临床测量。对374名年龄从6岁到成年的正常受试者测定了基频（SFF）和最低频率（LF）。男孩的SFF在8至10岁之间下降（从259赫兹降至247赫兹），而女孩则没有下降（253赫兹）。男孩和女孩的LF在6至10岁之间均下降（男孩从234赫兹降至203赫兹，女孩从230赫兹降至218赫兹），并且出现了性别差异。在青春期，与阴毛（PH）发育同时，男孩（分别降至100赫兹和90赫兹）和女孩（分别降至213赫兹和180赫兹）的SFF和LF均逐渐下降。总体而言，年轻的垂体功能减退儿童和患有特纳综合征的女孩SFF较高，而青春期前成熟延迟的男孩SFF较低。在一些产前生长发育迟缓的儿童中，SFF异常高。患有特纳综合征的女孩对雄激素表现出高度的（尽管个体有差异）声音敏感性；在出现任何其他男性化效应之前，她们的声音就变低了。该仪器有助于对生长发育迟缓综合征和青春期阶段进行特征描述。特别推荐用于监测雄激素治疗期间对声音的不良影响。
