出生后最初几天肥胖的Zucker（fa/fa）大鼠棕色脂肪组织线粒体中GDP结合减少的证据。
Evidence for decreased GDP binding to brown-adipose-tissue mitochondria of obese Zucker (fa/fa) rats in the very first days of life.
作者信息
Bazin R, Eteve D, Lavau M
出版信息
Biochem J. 1984 Jul 1;221(1):241-5. doi: 10.1042/bj2210241.
Abstract
GDP binding to brown-adipose-tissue mitochondria of obese Zucker-rat (fa/fa) pups aged 2-14 days was significantly less than in lean control rats. Scatchard analysis in 10-day-old pups suggests that there was a large decrease in GDP-binding sites. However, a significant increase in fat content in brown adipose tissue of 2-day-old pre-obese pups raised the question of the sequential order and causal relationship between these two derangements.
摘要
2至14日龄肥胖 Zucker 大鼠（fa/fa）幼崽棕色脂肪组织线粒体与GDP的结合显著少于瘦素对照大鼠。对10日龄幼崽进行的Scatchard分析表明，GDP结合位点大幅减少。然而，2日龄肥胖前期幼崽棕色脂肪组织中脂肪含量的显著增加引发了这两种紊乱之间顺序和因果关系的问题。
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