York D A, Al-Baker I
Biochem J. 1984 Oct 1;223(1):263-6. doi: 10.1042/bj2230263.
Corticotropin stimulated brown adipose tissue mitochondrial GDP binding of young obese rats to the levels seen in lean rats. This effect was attenuated by chronic increases in corticosterone. The stimulatory response to corticotropin was absent from lean rats unless endogenous secretion of corticosterone was prevented.
促肾上腺皮质激素可刺激年轻肥胖大鼠棕色脂肪组织线粒体的GDP结合,使其达到瘦大鼠的水平。这种效应会因皮质酮的长期增加而减弱。除非阻止皮质酮的内源性分泌,否则瘦大鼠对促肾上腺皮质激素没有刺激反应。