• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Decreased natural killer cell activity and interferon production by leucocytes in patients with adenocarcinoma of the pancreas.胰腺癌患者体内自然杀伤细胞活性降低，白细胞产生干扰素的能力下降。
Br J Cancer. 1984 Aug;50(2):231-3. doi: 10.1038/bjc.1984.168.
2
Human neonatal leukocyte interferon production and natural killer cytotoxicity in response to herpes simplex virus.人类新生儿白细胞对单纯疱疹病毒的干扰素产生及自然杀伤细胞毒性反应
J Interferon Res. 1983;3(4):461-3. doi: 10.1089/jir.1983.3.461.
3
Relationship between natural killer (NK) cells and interferon (IFN) alpha-producing cells in human peripheral blood. Studies with a monoclonal antibody with specificity for human natural killer cells.人类外周血中自然杀伤（NK）细胞与产生α干扰素（IFN）的细胞之间的关系。使用对人类自然杀伤细胞具有特异性的单克隆抗体进行的研究。
Immunobiology. 1984 Oct;167(4):359-64. doi: 10.1016/S0171-2985(84)80007-8.
4
Impact of interferon-alpha in combined chemoradioimmunotherapy for pancreatic adenocarcinoma (CapRI): first data from the immunomonitoring.α干扰素在胰腺癌联合放化疗免疫治疗（CapRI）中的作用：免疫监测的首批数据
J Immunother. 2007 Jan;30(1):108-15. doi: 10.1097/01.cji.0000211317.15278.27.
5
[Interferon-producing and cytotoxic activity of natural killer cells in multiple sclerosis patients].
Zh Nevropatol Psikhiatr Im S S Korsakova. 1987;87(2):211-5.
6
Transforming Growth Factor-β and Tumor Necrosis Factor-α Reduce the Sensitivity of MiaPaCa2 Pancreatic Cancer Cells to Lysis by NK Cells.转化生长因子-β和肿瘤坏死因子-α降低了MiaPaCa2胰腺癌细胞对自然杀伤细胞裂解的敏感性。
Bull Exp Biol Med. 2018 Jun;165(2):259-263. doi: 10.1007/s10517-018-4143-5. Epub 2018 Jun 20.
7
Characterization of Listeria monocytogenes-induced murine natural killer cells.单核细胞增生李斯特菌诱导的小鼠自然杀伤细胞的特性分析。
Immunol Res. 1986;5(1):50-60. doi: 10.1007/BF02917194.
8
Evaluation of the natural killer cell-interferon system in patients with mid-gut carcinoid tumours treated with leucocyte interferon.用白细胞干扰素治疗的中肠类癌肿瘤患者自然杀伤细胞-干扰素系统的评估
Clin Exp Immunol. 1983 Sep;53(3):716-24.
9
[Natural killer cell activity and thyroid cancer].[自然杀伤细胞活性与甲状腺癌]
Nihon Gan Chiryo Gakkai Shi. 1983 Aug 20;18(5):1101-7.
10
[Effect of different types of interferon on the natural cellular cytotoxicity of lung cancer patients].[不同类型干扰素对肺癌患者自然细胞毒性的影响]
Eksp Onkol. 1986;8(3):44-6.

引用本文的文献

1
The Role of Tumor Microenvironment in Pancreatic Cancer Immunotherapy: Current Status and Future Perspectives.肿瘤微环境在胰腺癌免疫治疗中的作用：现状与未来展望。
Int J Mol Sci. 2024 Sep 3;25(17):9555. doi: 10.3390/ijms25179555.
2
Suppression of the antitumoral activity of natural killer cells under indirect coculture with cancer-associated fibroblasts in a pancreatic TIME-on-chip model.在胰腺芯片上的肿瘤免疫微环境模型中，与癌症相关成纤维细胞间接共培养时自然杀伤细胞抗肿瘤活性的抑制。
Cancer Cell Int. 2023 Sep 27;23(1):219. doi: 10.1186/s12935-023-03064-9.
3
Immunotherapy and Pancreatic Cancer: A Lost Challenge?免疫疗法与胰腺癌：一项难以攻克的挑战？
Life (Basel). 2023 Jun 30;13(7):1482. doi: 10.3390/life13071482.
4
Microbiota Regulates Pancreatic Cancer Carcinogenesis through Altered Immune Response.微生物群通过改变免疫反应来调节胰腺癌的发生。
Microorganisms. 2023 May 8;11(5):1240. doi: 10.3390/microorganisms11051240.
5
Combinatorial immunotherapy with gemcitabine and ex vivo-expanded NK cells induces anti-tumor effects in pancreatic cancer.吉西他滨联合体外扩增 NK 细胞的组合免疫疗法可诱导胰腺癌产生抗肿瘤作用。
Sci Rep. 2023 May 11;13(1):7656. doi: 10.1038/s41598-023-34827-z.
6
The antitumor activity of hPRDX5 against pancreatic cancer and the possible mechanisms.hPRDX5 对胰腺癌的抗肿瘤活性及其可能机制。
Braz J Med Biol Res. 2022 Sep 12;55:e12324. doi: 10.1590/1414-431X2022e12324. eCollection 2022.
7
Immunotherapy in Pancreatic Cancer: Why Do We Keep Failing? A Focus on Tumor Immune Microenvironment, Predictive Biomarkers and Treatment Outcomes.胰腺癌的免疫疗法：我们为何屡战屡败？聚焦肿瘤免疫微环境、预测性生物标志物与治疗结果
Cancers (Basel). 2022 May 14;14(10):2429. doi: 10.3390/cancers14102429.
8
Current Limitations and Novel Perspectives in Pancreatic Cancer Treatment.胰腺癌治疗的当前局限与新视角
Cancers (Basel). 2022 Feb 16;14(4):985. doi: 10.3390/cancers14040985.
9
NK cells in pancreatic cancer demonstrate impaired cytotoxicity and a regulatory IL-10 phenotype.胰腺癌中的自然杀伤细胞表现出细胞毒性受损和调节性白细胞介素-10表型。
Oncoimmunology. 2020 Nov 19;9(1):1845424. doi: 10.1080/2162402X.2020.1845424.
10
The Immune Microenvironment in Pancreatic Cancer.胰腺癌中的免疫微环境。
Int J Mol Sci. 2020 Oct 3;21(19):7307. doi: 10.3390/ijms21197307.

本文引用的文献

1
Defective natural cytotoxicity in patients with cancer: normal number of effector cells but decreased recycling capacity in patients with advanced disease.癌症患者自然细胞毒性缺陷：效应细胞数量正常，但晚期疾病患者的再循环能力下降。
J Immunol. 1982 Nov;129(5):2255-9.
2
Evaluation of the natural killer cell-interferon system in patients with mid-gut carcinoid tumours treated with leucocyte interferon.用白细胞干扰素治疗的中肠类癌肿瘤患者自然杀伤细胞-干扰素系统的评估
Clin Exp Immunol. 1983 Sep;53(3):716-24.
3
Immunoregulation and natural killer cells.免疫调节与自然杀伤细胞
Mol Immunol. 1982 Oct;19(10):1313-21. doi: 10.1016/0161-5890(82)90299-1.
4
Regulation of human natural killing. I. The role of monocytes, interferon, and prostaglandins.人类自然杀伤的调节。I. 单核细胞、干扰素和前列腺素的作用。
J Immunol. 1981 Nov;127(5):2007-13.
5
Natural cytotoxicity and interferon production in human cancer: deficient natural killer activity and normal interferon production in patients with advanced disease.人类癌症中的自然细胞毒性和干扰素产生：晚期疾病患者自然杀伤活性缺陷及干扰素产生正常。
J Immunol. 1981 Nov;127(5):1817-22.
6
Interferons and the immune system.干扰素与免疫系统。
Nature. 1980 Apr 17;284(5757):593-5. doi: 10.1038/284593a0.
7
Decline of natural nonselective cell-mediated cytotoxicity in patients with tumor progression.肿瘤进展患者自然非选择性细胞介导细胞毒性的下降。
Cancer Res. 1977 Feb;37(2):413-8.
8
Spontaneous human lymphocyte-mediated cytotoxicity againts tumour target cells. I. The effect of malignant disease.人淋巴细胞对肿瘤靶细胞的自发细胞毒性。I. 恶性疾病的影响。
Int J Cancer. 1976 Nov 15;18(5):593-604. doi: 10.1002/ijc.2910180508.
9
A possible role of prostaglandins in the inhibition of natural and antibody-dependent cell-mediated cytotoxicity against tumor cells.前列腺素在抑制针对肿瘤细胞的天然及抗体依赖性细胞介导的细胞毒性中可能发挥的作用。
Cell Immunol. 1978 Aug;39(1):165-77. doi: 10.1016/0008-8749(78)90091-6.

Decreased natural killer cell activity and interferon production by leucocytes in patients with adenocarcinoma of the pancreas.

作者信息

Funa K, Nilsson B, Jacobsson G, Alm G V

出版信息

Br J Cancer. 1984 Aug;50(2):231-3. doi: 10.1038/bjc.1984.168.

DOI:10.1038/bjc.1984.168
PMID:6466540
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1976881/
Abstract
摘要