Thompson I M, Ernst J J, Gangai M P, Spence C R
J Urol. 1984 Oct;132(4):690-2. doi: 10.1016/s0022-5347(17)49828-4.
The results of routine urological screening of 2,005 men between 40 and 70 years old were reviewed. Digital rectal examination was used to screen for adenocarcinoma of the prostate. Of 65 nodules detected 17 proved to be adenocarcinoma. Clinical staging revealed no evidence of metastases in all but 2 patients but pathological (surgical) examination resulted in upstaging of disease in 66 per cent of the patients who underwent an operation. Digital rectal examination proved to be an insensitive screening device with poor predictive value. The use of adjunctive screening tools for detection of adenocarcinoma of the prostate is suggested.
对2005名年龄在40至70岁之间男性的常规泌尿外科筛查结果进行了回顾。采用直肠指检筛查前列腺腺癌。在检测出的65个结节中,17个被证实为腺癌。临床分期显示,除2例患者外,其余患者均无转移证据,但病理(手术)检查使66%接受手术的患者疾病分期上调。直肠指检被证明是一种敏感性低且预测价值差的筛查手段。建议使用辅助筛查工具来检测前列腺腺癌。