Siscovick D S, Weiss N S, Fletcher R H, Lasky T
N Engl J Med. 1984 Oct 4;311(14):874-7. doi: 10.1056/NEJM198410043111402.
To examine the risk of primary cardiac arrest during vigorous exercise, we interviewed the wives of 133 men without known prior heart disease who had had primary cardiac arrest. Cases were classified according to their activity at the time of cardiac arrest and the amount of their habitual vigorous activity. From interviews with wives of a random sample of healthy men, we estimated the amount of time members of the community spent in vigorous activity. Among men with low levels of habitual activity, the relative risk of cardiac arrest during exercise compared with that at other times was 56 (95 per cent confidence limits, 23 to 131). The risk during exercise among men at the highest level of habitual activity was also elevated, but only by a factor of 5 (95 per cent confidence limits, 2 to 14). However, among the habitually vigorous men, the overall risk of cardiac arrest--i.e., during and not during vigorous activity--was only 40 per cent that of the sedentary men (95 per cent confidence limits, 0.23 to 0.67). Although the risk of primary cardiac arrest is transiently increased during vigorous exercise, habitual vigorous exercise is associated with an overall decreased risk of primary cardiac arrest.
为了研究剧烈运动期间原发性心脏骤停的风险，我们采访了133名既往无已知心脏病史但发生过原发性心脏骤停的男性的妻子。根据心脏骤停时的活动情况以及习惯性剧烈活动量对病例进行分类。通过对随机抽取的健康男性妻子的访谈，我们估算了社区成员进行剧烈活动的时间。在习惯性活动水平较低的男性中，运动期间心脏骤停的相对风险与其他时间相比为56（95%置信区间为23至131）。习惯性活动水平最高的男性在运动期间的风险也有所升高，但仅为5倍（95%置信区间为2至14）。然而，在习惯性剧烈运动的男性中，心脏骤停的总体风险（即剧烈活动期间和非剧烈活动期间）仅为久坐男性的40%（95%置信区间为0.23至0.67）。虽然剧烈运动期间原发性心脏骤停的风险会短暂增加，但习惯性剧烈运动与原发性心脏骤停的总体风险降低有关。
