识别牙龈卟啉单胞菌特异性和交叉反应性抗原的单克隆抗体的制备。
Production of monoclonal antibodies that recognize specific and cross-reactive antigens of Bacteroides gingivalis.
作者信息
Hanazawa S, Saitoh K, Ohmori Y, Nishihara H, Fujiwara S, Kitano S
出版信息
Infect Immun. 1984 Oct;46(1):285-7. doi: 10.1128/iai.46.1.285-287.1984.
Abstract
Four monoclonal antibodies directed against Bacteroides gingivalis were established by hybridoma technology. Their reactivity against B. gingivalis, Bacteroides intermedius, and Bacteroides melaninogenicus was detected by the enzyme-linked immunosorbent assay. Three monoclonal antibodies specifically reacted with B. gingivalis. One recognized antigens that were cross-reactive between B. gingivalis and B. intermedius. These monoclonal antibodies provide new tools for antigenic analysis of B. gingivalis.
摘要
通过杂交瘤技术制备了四种针对牙龈卟啉单胞菌的单克隆抗体。采用酶联免疫吸附测定法检测了它们对牙龈卟啉单胞菌、中间普氏菌和产黑色素普氏菌的反应性。三种单克隆抗体与牙龈卟啉单胞菌特异性反应。一种识别牙龈卟啉单胞菌和中间普氏菌之间具有交叉反应性的抗原。这些单克隆抗体为牙龈卟啉单胞菌的抗原分析提供了新工具。
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