特布他林气雾剂的支气管扩张作用。
Bronchodilating effect of terbutaline aerosol.
作者信息
Chester E H, Doggett W E, Montenegro H D, Schwartz H J, Jones P K
出版信息
Clin Pharmacol Ther. 1978 Jun;23(6):630-4. doi: 10.1002/cpt1978236630.
We compared the efficacy of terbutaline with that of metaproterenol, isoproterenol, and placebo aerosols in 16 asthmatic patients. Terbutaline, metaproterenol, and isoproterenol produced equivalent improvements in flow rates. At 5 hr, the effect of terbutaline on tests of small airways, FEF25%--75%, and FEF50%, was greater (p less than 0.05) than that of metaproterenol and isoproterenol. Terbutaline produced no significant change of heart rate or blood pressure.
我们比较了特布他林与间羟异丙肾上腺素、异丙肾上腺素及安慰剂气雾剂对16例哮喘患者的疗效。特布他林、间羟异丙肾上腺素和异丙肾上腺素对流速的改善效果相当。在5小时时，特布他林对小气道测试指标（FEF25% - 75%和FEF50%）的作用比间羟异丙肾上腺素和异丙肾上腺素更强（p < 0.05）。特布他林对心率和血压无显著影响。
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