Merimsky E, Orni-Wasserlauf R, Yust I
Urol Res. 1984;12(3):179-82. doi: 10.1007/BF00255919.
A necrotic torted testis left in the scrotum affects the contralateral testis, resulting in depressed fertility. It was suggested that testicular torsion provoked a systemic response of an immunologic nature. In order to prove this theory, 56 rats were operated. Ten had a sham operation, in 17 a testis was torted and excised after 24 h, and in 29 a testis was torted and excised after 24 h, and in 29 a testis was torted but left in situ till the sacrifice. Antisperm-antibodies were not found in any phase of the experiment in the sham group. Using indirect immunofluorescence, antisperm-antibodies were found in the sera of 8/17 rats of the orchiectomy group and in 24/29 of the detorted group. In the direct immunofluorescence study, all the antibodies were localized in the tail of the spermatozoid. The antisperm-antibodies disappeared after 3 to 6 months.
留在阴囊内的坏死扭转睾丸会影响对侧睾丸，导致生育能力下降。有人提出睾丸扭转会引发免疫性质的全身反应。为了证明这一理论，对56只大鼠进行了手术。10只进行假手术，17只睾丸扭转24小时后切除，29只睾丸扭转24小时后切除，还有29只睾丸扭转但留在原位直至处死。假手术组在实验的任何阶段均未发现抗精子抗体。使用间接免疫荧光法，在睾丸切除组的17只大鼠中有8只血清中发现抗精子抗体，在扭转复位组的29只中有24只发现。在直接免疫荧光研究中，所有抗体都定位在精子尾部。抗精子抗体在3至6个月后消失。
