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[胰腺完全切除及其切除术后睾丸的结构变化]

[Structural changes in the testis in complete removal of the pancreas and its resection].

作者信息

Poliak R I, Krishtopin V S

出版信息

Biull Eksp Biol Med. 1984 Sep;98(9):351-4.

PMID:6487795
Abstract

The dog pancreas was resected completely or partially. The morphofunctional status of the testicle was examined at varying times after operation with the use of histological, histochemical and morphometric tests. The alterations discovered attest to the dependence of the structural shifts in the testicle on the type of surgery on the pancreas. Resection of the end parts caused temporary and insignificant changes in the testis. Resection of the central part with ligation and intersection of the main excretory ducts gave rise to dystrophic changes in the spermatogenic epithelium, disorders in the structural elements responsible for hormonal activity. Complete resection of the pancreas was early in affecting the morphofunctional status of the testicle. Ten to 15 days after operation profound dystrophic and atrophic changes were detectable in all the cells of the testicle. Injection of insulin postponed the animal's death, decelerated but not prevented the development of regressive changes in the testis.

摘要

狗的胰腺被全部或部分切除。术后不同时间,通过组织学、组织化学和形态计量学检测来检查睾丸的形态功能状态。所发现的改变证明了睾丸结构变化对胰腺手术类型的依赖性。切除胰腺末端部分会导致睾丸出现暂时且不明显的变化。切除胰腺中央部分并结扎和切断主要排泄导管会导致生精上皮发生营养不良性变化,负责激素活性的结构元件出现紊乱。胰腺完全切除会较早影响睾丸的形态功能状态。术后10至15天,在睾丸的所有细胞中都可检测到严重的营养不良和萎缩性变化。注射胰岛素可推迟动物死亡,减缓但不能阻止睾丸退行性变化的发展。

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Biull Eksp Biol Med. 1984 Sep;98(9):351-4.
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