Schwarz A, Keller F, Seyfert S, Pöll W, Molzahn M, Distler A
Clin Nephrol. 1984 Sep;22(3):133-7.
One hundred and forty-five patients on hemodialysis for periods of 1 month to 16 years were examined clinically for carpal tunnel syndrome (CTS). Typical symptoms and clinical manifestations of symptomatic CTS, either unilaterally or in both hands, were detected in 21 of these patients (15%). In contrast to the classic form of CTS, hemodialysis CTS in our patients was frequently accompanied by Raynaud's phenomenon of those digits supplied by the median nerve. A highly significant correlation was established between the incidence of CTS and the duration of dialysis (p less than 0.001). The association of CTS with analgesic nephropathy was significantly higher (52%) than with other kidney diseases (p less than 0.034). Immediate relief of pain was achieved after carpal tunnel release (11 releases) in 8 of the 21 patients. Sensory and motor function was gradually, but often only partially, restored. Unoperated CTS progressed to loss of sensory and motor function within 1 to 4 years after the onset of symptoms. CTS should be considered a major late complication in patients on chronic hemodialysis.
对145例接受血液透析1个月至16年的患者进行了腕管综合征（CTS）的临床检查。在这些患者中，有21例（15%）检测到有症状的CTS的典型症状和临床表现，症状为单侧或双手出现。与经典形式的CTS不同，我们患者中的血液透析相关性CTS常伴有正中神经支配手指的雷诺现象。CTS的发生率与透析时间之间建立了高度显著的相关性（p<0.001）。CTS与镇痛剂肾病的关联显著高于其他肾脏疾病（52%，p<0.034）。21例患者中有8例（11次手术）在腕管松解术后疼痛立即缓解。感觉和运动功能逐渐恢复，但往往只是部分恢复。未手术的CTS在症状出现后1至4年内进展为感觉和运动功能丧失。CTS应被视为慢性血液透析患者的一种主要晚期并发症。
