Schwartz H J, Chester E H
J Allergy Clin Immunol. 1984 Oct;74(4 Pt 1):511-3. doi: 10.1016/0091-6749(84)90387-7.
Eight asthmatic patients with a history suggestive of sulfite sensitivity were studied, six of whom had a positive oral challenge to doses from 10 mg to 50 mg. All eight patients had aerosol metabisulfite challenge; six positive tests were observed at doses of 0.5 mg/ml and 5.0 mg/ml. Aerosolizing solutions of metabisulfite at 5.0 mg/ml generated significant amounts of free sulfur dioxide. Implications of these findings are discussed.
对8名有亚硫酸盐敏感性病史的哮喘患者进行了研究，其中6人对10毫克至50毫克剂量的口服激发试验呈阳性。所有8名患者均进行了焦亚硫酸气雾激发试验；在0.5毫克/毫升和5.0毫克/毫升剂量下观察到6次阳性试验。5.0毫克/毫升的焦亚硫酸雾化溶液产生了大量游离二氧化硫。讨论了这些发现的意义。
