Karunanayake E H, Welihinda J, Sirimanne S R, Sinnadorai G
J Ethnopharmacol. 1984 Jul;11(2):223-31. doi: 10.1016/0378-8741(84)90040-0.
Investigations were carried out to evaluate the oral hypoglycaemic activity of some Sri Lankan medicinal plants. Approximately 40 plants available locally are reputed to have oral hypoglycaemic activity. Of these, the mostly widely used are (a) Salacia reticulata (Celastraceae) (b) Aegle marmelos (Rutaceae) and (c) Momordica charantia (Cucurbitaceae). Aqueous decoctions of these plants were investigated for their ability to lower the fasting blood glucose level and improve the glucose tolerance in laboratory animals. The results indicate that the aqueous decoctions of all three plants possess significant hypoglycaemic effect. The magnitude of this effect showed time related variation with the three plants. The highest oral hypoglycaemic activity and the maximum improvement of the oral glucose tolerance were associated with the extract of Momordica charantia while the least but significant effects were shown by Salacia reticulata.
为评估一些斯里兰卡药用植物的口服降血糖活性展开了研究。当地约有40种植物据说具有口服降血糖活性。其中，使用最为广泛的是：(a) 网脉五层龙（刺茉莉科）；(b) 印度枳（芸香科）；(c) 苦瓜（葫芦科）。对这些植物的水煎剂降低实验动物空腹血糖水平及改善葡萄糖耐量的能力进行了研究。结果表明，这三种植物的水煎剂均具有显著的降血糖作用。这种作用的程度随这三种植物呈现出与时间相关的变化。苦瓜提取物具有最高的口服降血糖活性及对口服葡萄糖耐量的最大改善作用，而网脉五层龙的作用最小，但也具有显著性。
