Barregård L, Axelsson A
Scand Audiol. 1984;13(3):151-5. doi: 10.3109/01050398409043054.
A review of the literature and four case reports are presented. The patients had all been exposed to noise as well as to organic solvents and they demonstrate a much more pronounced sensorineural hearing loss than would be expected from their noise exposure only. In one of the cases a psycho-organic syndrome due to solvent exposure was verified. Audiograms from 32 painters in a shipyard who had been exposed to noise and solvents did not, however, show any clustering of inexplicably pronounced sensorineural hearing losses. With reference to the above cases it is suggested that there might be a possibility of an ototraumatic interaction between solvents and noise. In view of the neurotoxic effects of organic solvents, such an interaction is conceivable.
本文呈现了文献综述及四例病例报告。这些患者均暴露于噪音和有机溶剂环境中,且他们表现出的感音神经性听力损失比仅由噪音暴露所预期的更为明显。其中一例经证实存在因溶剂暴露导致的精神器质性综合征。然而,对某造船厂32名暴露于噪音和溶剂环境的油漆工所做的听力图检查,并未显示出存在任何原因不明的明显感音神经性听力损失聚集现象。鉴于上述病例,有人提出溶剂与噪音之间可能存在耳创伤性相互作用。考虑到有机溶剂的神经毒性作用,这种相互作用是可以想象的。