Nyström M, Peräsalo J
Scand J Infect Dis. 1984;16(3):235-9. doi: 10.3109/00365548409070395.
At the Finnish Student Health Service, we have measured rubella antibodies in 3 consecutive academic years--1979-80, 1980-81 and 1981-82--in 2 483 first year female students. In 1979-80, 16.4% were seronegative, the following year the figures were 10.4% and in the third year 7.4%. Among students less than or equal to 19 yr of age the seronegatives decreased from 19 to 2% in 3 yr. This decrease shows that the national rubella vaccination programme which began in 1975 has been more successful than expected. A hemolysis-in-gel (HIG) test has proved a suitable screening method and the health examination of first year students a suitable occasion to test the immunity against rubella. Seroconversion occurred in 81.4% of those vaccinated.
在芬兰学生健康服务中心,我们在连续三个学年(1979 - 1980年、1980 - 1981年和1981 - 1982年)对2483名一年级女学生进行了风疹抗体检测。1979 - 1980年,16.4%的学生血清学检测呈阴性,次年这一数字为10.4%,第三年为7.4%。在年龄小于或等于19岁的学生中,血清学检测呈阴性的比例在3年内从19%降至2%。这种下降表明始于1975年的全国风疹疫苗接种计划比预期更为成功。凝胶内溶血(HIG)试验已被证明是一种合适的筛查方法,而一年级学生的健康检查是检测风疹免疫力的合适时机。接种疫苗的学生中81.4%发生了血清转化。