Strain G M, Barta O, Olcott B M, Braun W F
Am J Vet Res. 1984 Sep;45(9):1812-3.
Determinations were made by laser nephelometry of serum and CSF immunoglobulin (Ig) G concentrations in Suffolk sheep with naturally occurring scrapie. The serum IgG concentrations in 3 sheep with confirmed or suspected scrapie were between 2,140 and 3,290 mg of IgG/100 ml, and the CSF values were between less than 10 and 75 mg of IgG/100 ml. In 8 clinically healthy (control) sheep, serum IgG concentrations were 2,647 to 7,380 mg/100 ml and CSF IgG concentrations were between 0 (undetectable) and 162 mg/100 ml. A sheep with pulmonary adenomatosis had 1,445 mg of IgG/100 ml of serum. The results indicated that neither serum nor CSF IgG concentrations were increased in sheep with naturally occurring infection with scrapie and that the severity of the disease did not correspond with the IgG concentration.
采用激光散射比浊法测定了自然感染羊瘙痒病的萨福克绵羊血清和脑脊液免疫球蛋白（Ig）G浓度。3只确诊或疑似感染羊瘙痒病的绵羊血清IgG浓度在2140至3290mg IgG/100ml之间，脑脊液中IgG浓度在低于10至75mg IgG/100ml之间。8只临床健康（对照）绵羊的血清IgG浓度为2647至7380mg/100ml，脑脊液IgG浓度在0（检测不到）至162mg/100ml之间。一只患有肺腺瘤病的绵羊血清IgG浓度为1445mg/100ml。结果表明，自然感染羊瘙痒病的绵羊血清和脑脊液IgG浓度均未升高，且疾病严重程度与IgG浓度不相关。
