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[利用新的实验模型——纤连蛋白结合试验评估生物玻璃的生物相容性]

[Evaluation of the biological compatibility of bioglass with a new experimental model, the fibronectin binding test].

作者信息

Cannas M, Amedeo M R, Portigliatti-Barbos M

出版信息

Boll Soc Ital Biol Sper. 1984 Aug 31;60(8):1515-9.

PMID:6497986
Abstract

The authors expose their results about the biological compatibility of Bioglass (BG), using a new experimental model; this model implicates the use of Fibronectin (FN), a glycoprotein involved in cellular adhesion. The term Bioglass indicates a family of glasses (of possible use as implants) with the formation of a stable calcium-phosphate film on their surface when in contact with an aqueous environment. Two types of BG, B5 and B6, have been incubated with FN; the first binds three times B6 the FN. The results are discussed considering other preliminary results.

摘要

作者们采用一种新的实验模型公布了他们关于生物玻璃(BG)生物相容性的研究结果;该模型涉及使用纤连蛋白(FN),一种参与细胞黏附的糖蛋白。术语生物玻璃指的是一类玻璃(可作为植入物使用),当与水性环境接触时,其表面会形成稳定的磷酸钙膜。两种类型的BG,即B5和B6,已与FN一起孵育;第一种结合的FN是B6的三倍。结合其他初步结果对这些结果进行了讨论。

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