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出生体重的父母决定因素。

Parental determinants of birth weight.

作者信息

Magnus P, Berg K, Bjerkedal T, Nance W E

出版信息

Clin Genet. 1984 Nov;26(5):397-405. doi: 10.1111/j.1399-0004.1984.tb01079.x.

DOI:10.1111/j.1399-0004.1984.tb01079.x
PMID:6499253
Abstract

As part of a study on causes of variation in birth weight, questionnaire data on parental measures were related to offspring birth weights recorded in the Medical Birth Registry of Norway. A genetic analysis of parent-offspring covariances in birth weight indicated that about 60% of the variance in birth weight could be explained by effects of fetal genes, while no effects of maternal genes were detectable. Multiple regression analysis showed that height and weight of both parents and maternal smoking status were associated with variation in birth weight. Socioeconomic status, educational attainment and paternal smoking habit had no independent effects. The adult, parental variables could only explain 10% of the variation in mean offspring birth weight.

摘要

作为一项关于出生体重变异原因研究的一部分,将父母测量指标的问卷数据与挪威医学出生登记处记录的后代出生体重相关联。对出生体重的亲子协方差进行的遗传分析表明,出生体重变异的约60%可由胎儿基因效应解释,而未检测到母体基因的效应。多元回归分析表明,父母双方的身高和体重以及母亲的吸烟状况与出生体重的变异有关。社会经济地位、教育程度和父亲的吸烟习惯没有独立影响。成年父母变量只能解释后代平均出生体重变异的10%。

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