Cnattingius S, Axelsson O, Eklund G, Lindmark G
Early Hum Dev. 1984 Sep;10(1-2):35-44. doi: 10.1016/0378-3782(84)90109-9.
In a prospective clinical study from Uppsala County, Sweden, in 1980, all pregnancies were screened early in pregnancy for 15 previously reported risk factors for intrauterine growth retardation (IUGR). This risk group (n = 639) was then compared with a randomly selected control group (n = 539). In the risk group, there were increased risks for the delivery of growth retarded infants, low birthweight infants and infants spontaneously delivered as prematures. 30% of the population exhibited risk factors. Smoking was the most important risk factor, 16% of the mothers smoked at least ten cigarettes per day and smoking was the main risk factor in the majority of cases with IUGR.
1980年，在瑞典乌普萨拉县进行的一项前瞻性临床研究中，对所有孕妇在妊娠早期进行了筛查，以检测先前报道的15种宫内生长受限（IUGR）风险因素。然后将这个风险组（n = 639）与随机选择的对照组（n = 539）进行比较。在风险组中，出生发育迟缓婴儿、低体重婴儿和早产自发分娩婴儿的风险增加。30%的人群存在风险因素。吸烟是最重要的风险因素，16%的母亲每天至少吸10支烟，并且在大多数宫内生长受限病例中，吸烟是主要风险因素。
