[Effect of ceruloplasmin on the growth of experimental tumors and proliferative activity of cells].

Exogenous ceruloplasmin influence on experimental tumour growth and intensity of normal and malignant cell proliferation in tissue culture was investigated. It was found that ceruloplasmin administration to animals with transplanted tumours caused a 25-50% inhibition of tumour growth. A growth inhibiting activity of ceruloplasmin observed in tissue culture at the concentration of 5 mg/ml was established. It is also shown that ceruloplasmin did not reduce the antitumour effect of cyclophosphamide.