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膦甲酸对非洲猪瘟(ASF病毒)复制的抑制作用

Inhibition of African swine fever (ASF virus replication by phosphonoacetic acid.

作者信息

Moreno M A, Carrascosa A L, Ortín J, Viñuela E

出版信息

J Gen Virol. 1978 May;39(2):253-8. doi: 10.1099/0022-1317-39-2-253.

Abstract

Phosphonoacetic acid (PAA) inhibits the multiplication of African swine fever (ASF) virus in VERO cells. The observed inhibition of the in vivo DNA synthesis could be related to the in vitro inhibition of a virus-induced DNA polymerase activity present in cytoplasmic extracts from infected VERO cells.

摘要

膦乙酸(PAA)可抑制非洲猪瘟(ASF)病毒在VERO细胞中的增殖。观察到的体内DNA合成抑制可能与体外抑制感染的VERO细胞胞质提取物中存在的病毒诱导的DNA聚合酶活性有关。

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