Morat M, Dufaure J P
C R Seances Soc Biol Fil. 1980;173(6):1078-82.
Study of the profile of androstenedione, testosterone and dihydrotestosterone elaboration was performed till 23 days of culture. Stimulation by hCG went through several phases which were expressed in terms of hormonal elaboration by successive steps of 1) progressive initiation 2) strong activity 3) fall 4) renewal of the secretion. The inital step corresponds to the restoration of cytoplasmic organels dealing with steroidogenesis. The fall could correspond to apparition of a transient refractoriness. This late event resembles desensitization which has been described in another models.
对雄烯二酮、睾酮和双氢睾酮合成情况的研究持续至培养的第23天。人绒毛膜促性腺激素（hCG）刺激经历了几个阶段，这些阶段通过激素合成的连续步骤表现为：1）渐进性启动；2）强活性；3）下降；4）分泌恢复。初始步骤对应于处理类固醇生成的细胞质细胞器的恢复。下降可能对应于短暂不应性的出现。这一后期事件类似于在其他模型中描述的脱敏现象。
