Révész L, Siracka E
Strahlentherapie. 1984 Nov;160(11):658-60.
Retrospective, morphometric analysis of histological preparations from cervical cancers indicate that the stromal component of the neoplastic tissue is richer in vascular elements in the cases in which the patients have a prolonged survival after radiotherapy. The finding supports earlier observations which indicate a relationship between intercapillary distance and radiocurability of cervical cancers. The routine determination of a vascularity index V, denoting the grade of vascular density in the neoplastic tissue, is suggested as a complementary parameter for the classification of tumours. Access to such an index could promote a more individualized tumor therapy, especially in regard to the control of radioresistant, hypoxic cells.
对宫颈癌组织学标本进行的回顾性形态学分析表明，在放疗后患者生存期延长的病例中，肿瘤组织的间质成分富含血管成分。这一发现支持了早期的观察结果，即毛细血管间距与宫颈癌的放射可治愈性之间存在关联。建议常规测定血管指数V，该指数表示肿瘤组织中的血管密度等级，作为肿瘤分类的补充参数。获得这样一个指数有助于促进更个体化的肿瘤治疗，特别是在控制放射抗性缺氧细胞方面。
