Toranzo A E, Combarro P, Lemos M L, Barja J L
Appl Environ Microbiol. 1984 Oct;48(4):872-7. doi: 10.1128/aem.48.4.872-877.1984.
The occurrence of drug resistance and plasmid-mediated transferability was investigated in 170 strains belonging to eight bacterial groups isolated from cultured rainbow trout. It was found that 87.6% of the strains were resistant to at least one drug, with the highest percentages of resistance being detected for ampicillin (54.7%), sulfadiazine (46.5%), nitrofurantoin (38.2%), and chloramphenicol (37.0%). Six enterobacteria, two Vibrio, and one Aeromonas isolate transferred resistance factors to Escherichia coli K-12. The most common transmissible R factor determined resistance to chloramphenicol and sulfadiazine, demonstrating an association between a specific plasmid and the resistance pattern transferred. The presence of chloramphenicol in fish food was detected by bioassay. In general, transfer frequencies were similar in primary and secondary matings, which indicate the potential water-borne dissemination of these R plasmids.
对从养殖虹鳟鱼分离出的属于八个细菌类群的170株菌株进行了耐药性和质粒介导转移性的研究。结果发现，87.6%的菌株对至少一种药物耐药，氨苄西林（54.7%）、磺胺嘧啶（46.5%）、呋喃妥因（38.2%）和氯霉素（37.0%）的耐药率最高。六株肠杆菌、两株弧菌和一株气单胞菌分离株将耐药因子转移到大肠杆菌K-12。最常见的可转移R因子决定了对氯霉素和磺胺嘧啶的耐药性，表明特定质粒与转移的耐药模式之间存在关联。通过生物测定法检测到鱼食中存在氯霉素。一般来说，初次交配和二次交配的转移频率相似，这表明这些R质粒有通过水传播的可能性。
