Benoni C, Nilsson A
Scand J Gastroenterol. 1984 Sep;19(6):824-30.
The proportion of smokers in this study was significantly lower among patients with ulcerative colitis (13%) than among patients with Crohn's disease (47%), the difference being significant for both sexes and for the age groups both below and above 40 years. The proportion of male ex-smokers among patients with ulcerative colitis (28%) was higher than among patients with Crohn's disease (8%), whereas the proportions of non-smokers differed less. Many of the patients with ulcerative colitis who had a late onset were male ex-smokers. The smoking patients with ulcerative colitis were mainly women. They smoked less than the smoking patients with Crohn's disease and less than the ex-smokers in each group. No smoking patient with ulcerative colitis smoked greater than 20 cigarettes/day. In the group of male ex-smokers with ulcerative colitis, there was an accumulation of onsets during the 4 years after the definitive smoking stop. The number of colectomies performed on patients with ulcerative colitis did not vary with smoking habits. In the group of ex-smokers the colectomy was performed after the smoking stop in 19 out of 20 patients.
本研究中,溃疡性结肠炎患者的吸烟比例(13%)显著低于克罗恩病患者(47%),这一差异在男女两性以及40岁以下和40岁以上年龄组中均具有显著性。溃疡性结肠炎患者中男性戒烟者的比例(28%)高于克罗恩病患者(8%),而非吸烟者的比例差异较小。许多起病较晚的溃疡性结肠炎患者为男性戒烟者。溃疡性结肠炎吸烟患者主要为女性。她们的吸烟量低于克罗恩病吸烟患者,也低于每组中的戒烟者。没有溃疡性结肠炎吸烟患者每天吸烟超过20支。在溃疡性结肠炎男性戒烟者组中,确诊戒烟后的4年期间发病出现聚集现象。溃疡性结肠炎患者接受结肠切除术的数量与吸烟习惯无关。在戒烟者组中,20例患者中有19例在戒烟后接受了结肠切除术。