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血清中对乙酰氨基酚的比色测定法。

Colorimetric assay for acetaminophen in serum.

作者信息

Shihabi Z K, David R M

出版信息

Ther Drug Monit. 1984;6(4):449-53. doi: 10.1097/00007691-198412000-00012.

Abstract

A colorimetric method for determination of acetaminophen in serum, based on its reaction with 2-nitroso-1-naphthol-4-sulfonic acid, is described. The method is sensitive, rapid, and free from the interferences of serum matrix and most common drugs. The method can be performed manually or can be semiautomated. The results from this method correlate well with values determined by high-performance liquid chromatography.

摘要

描述了一种基于对乙酰氨基酚与2-亚硝基-1-萘酚-4-磺酸反应的血清中对乙酰氨基酚比色测定法。该方法灵敏、快速,不受血清基质和大多数常用药物的干扰。该方法可手动操作,也可半自动操作。该方法的结果与高效液相色谱法测定的值相关性良好。

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