Christoffersson J O, Schütz A, Ahlgren L, Haeger-Aronsen B, Mattsson S, Skerfving S
Am J Ind Med. 1984;6(6):447-57. doi: 10.1002/ajim.4700060608.
In 75 active lead workers the median lead level in finger-bone (bone-Pb), as determined in vivo by an X-ray fluorescence method, was 43 micrograms/g (range less than 20-122). In 32 retired workers the median level was even higher, 59 micrograms/g (range less than 20-135), which indicates a slow turnover rate of lead in finger-bone. This was confirmed in 18 of the "active" workers, in whom bone-Pb was studied in connection with an exposure-free period. In spite of a significant decrease in blood-lead levels (B-Pb), no systematic change of bone-Pb occurred. There was an increase of bone-Pb with time of employment, but with a large interindividual variation. No association was found between bone-Pb and present B-Pb in the active lead workers. However, in the retired ones, B-Pb rose with increasing bone-Pb. The bone-lead pool thus causes an "internal" lead exposure.
在75名在职铅作业工人中，通过X射线荧光法体内测定的指骨铅水平（骨铅）中位数为43微克/克（范围小于20 - 122）。在32名退休工人中，中位数水平更高，为59微克/克（范围小于20 - 135），这表明指骨中铅的周转速度较慢。在18名“在职”工人中得到了证实，他们在无暴露期对骨铅进行了研究。尽管血铅水平（B - Pb）显著下降，但骨铅没有发生系统性变化。骨铅随就业时间增加，但个体间差异很大。在职铅作业工人的骨铅与当前血铅之间未发现关联。然而，在退休工人中，血铅随骨铅增加而升高。骨铅库因此导致“内部”铅暴露。
